[HTML][HTML] A binding question: the evolution of the receptor concept
AH Maehle - Endeavour, 2009 - Elsevier
In present-day pharmacology and medicine, it is usually taken for granted that cells contain
a host of highly specific receptors. These are defined as proteins on or within the cell that …
a host of highly specific receptors. These are defined as proteins on or within the cell that …
[图书][B] Principles and methods in receptor binding
F Cattabeni - 2013 - books.google.com
One of the major advances in the understanding of the mechanism of action of hormones,
neurotransmitters and drugs had arisen from the hypothesis that the physiological or …
neurotransmitters and drugs had arisen from the hypothesis that the physiological or …
The use of affinity labels in the identification of receptors
SJ Singer, A Ruoho, H Kiefer, J Lindstrom, ES Lennox - Drug receptors, 1973 - Springer
Most drug and hormone receptors that are membrane bound are in the category of
'integral'membrane proteins (Singer, 1971; Singer & Nicolson, 1972); that is, they are not …
'integral'membrane proteins (Singer, 1971; Singer & Nicolson, 1972); that is, they are not …
Drugs and cells—pioneering the concept of receptors
CR Prüll, AH Maehle, RF Halliwell - Pharmacy in history, 2003 - JSTOR
X his paper discusses the emergence of the idea of the drug receptor, a concept that has
become increasingly important in the biomédical and pharmaceutical sciences over the past …
become increasingly important in the biomédical and pharmaceutical sciences over the past …
Membrane receptors, cyclic nucleotides, and transport
SA Rudolph, RJ Lefkowitz - Concepts and Models, 1978 - Springer
Membrane Receptors, Cyclic Nucleotides, and Transport Page 1 Chapter 10 Membrane
Receptors, Cyclic Nucleotides, and Transport SA RUDOLPH and R. J. LEFKOWITZ A. Introduction …
Receptors, Cyclic Nucleotides, and Transport SA RUDOLPH and R. J. LEFKOWITZ A. Introduction …
Membrane transport
DL Oxender - Annual Review of Biochemistry, 1972 - annualreviews.org
The presence of a large variety of more or less specific transport systems in the cytoplasmic
membrane of living cells has long been established. It is generally believed that these …
membrane of living cells has long been established. It is generally believed that these …
Critique of current views on receptors, and a new general theory of receptor location and action in vivo
H Hillman - Medical Hypotheses, 1988 - Elsevier
Abstract The Davson-Danielli model of the cell membrane accounted for nearly all the space
within it by suggesting that it was composed of structural proteins and lipids; this would leave …
within it by suggesting that it was composed of structural proteins and lipids; this would leave …
Cell receptors
SA Kaplan - American Journal of Diseases of Children, 1984 - jamanetwork.com
The scheme of evolution required the specialization of parts or organs of the body to
undertake discrete functions, eg, the muscles provide locomotion, the gut digests and …
undertake discrete functions, eg, the muscles provide locomotion, the gut digests and …
[图书][B] Receptors in the Nervous System: Volume 6
A Lajtha - 2013 - books.google.com
A major advance in the biological sciences in the past decade has been the biochemical
identification of cell membrane receptors. The existence of re ceptor substances on the …
identification of cell membrane receptors. The existence of re ceptor substances on the …