Background: Lifestyle intervention and metformin have been shown to prevent diabetes;
however, their efficacy in preventing cardiovascular disease associated with the …

Diabet. Med. 30, 46–55 (2013) Abstract Aims Whether long‐term cardiovascular risk is
reduced by the Diabetes Prevention Program interventions is unknown. The aim of this study …

The largest and longest clinical trial of metformin for the prevention of diabetes is the
Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study …

This review describes the effect of lifestyle change or metformin compared with standard
care on incident type 2 diabetes and cardiometabolic risk factors in the Diabetes Prevention …

OBJECTIVE To determine whether metformin or lifestyle modification can lower rates of all-
cause and cause-specific mortality in the Diabetes Prevention Program and Diabetes …

OBJECTIVE—The Diabetes Prevention Program demonstrated the ability to delay or prevent
type 2 diabetes in participants with impaired glucose tolerance (IGT). Participants with IGT …

Objective To summarize the results of the Diabetes Prevention Program (DPP) and describe
the additional 5-year follow-up study. Methods The design, implementation, and outcome of …

OBJECTIVE We examined the effects of metformin on diabetes prevention and the
subgroups that benefited most over 15 years in the Diabetes Prevention Program (DPP) and …

We have conducted a narrative review based on a structured search strategy, focusing on
the effects of metformin on the progression of non-diabetic hyperglycemia to clinical type 2 …

Introduction Although the Diabetes Prevention Program and other clinical trials
demonstrated the efficacy of intensive lifestyle interventions (ILI) and metformin to prevent …