This study explored the impact of gold nanoparticles on the metabolic activity and
morphology of human pulmonary endothelial cell monolayers. We developed a gold …

In this work, we evaluated the impact of gold nanoparticles on endothelial cell behavior and
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …

Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …

The development of engineered nanomaterials is growing exponentially, despite concerns
over their potential similarities to environmental nanoparticles that are associated with …

Cytotoxicity of nanoparticles, typically evaluated by biochemical-based assays, often
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …

The impact of nanoparticles (NPs) in medicine and biology has increased rapidly in recent
years. Gold NPs have advantageous properties such as chemical stability, high electron …

PEGylated gold nanoparticles (AuNPs) have an extended circulation time after intravenous
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …

Surface functionalization of nanoparticles (NPs) may alter their biological interactions such
as uptake by alveolar macrophages (AMs). Pulmonary delivery of gold NPs (Au NPs) has …

Background The lung represents the primary entry route for airborne particles into the
human body. Most studies addressed possible adverse effects using single (nano) particles …

Background The use of gold nanoparticles (AuNPs) for diagnostic applications and for drug
and gene-delivery is currently under intensive investigation. For such applications …