Lipoprotein (a): relation to other risk factors and genetic heritability. Results from a Dutch parent-twin study

DI Boomsma, A Kaptein, HJM Kempen, JAG Leuven… - Atherosclerosis, 1993 - Elsevier
We measured plasma levels of lipoprotein (a)(Lp (a)) in a sample of 152 Dutch adolescent
mono-and dizygotic twin pairs and their parents. The distribution of Lp (a) levels was …

Genetic control of lipoprotein (a) concentrations is different in Africans and Caucasians

M Scholz, HG Kraft, A Lingenhel, R Delport… - European Journal of …, 1999 - nature.com
Abstract Lipoprotein (a)(Lp (a)) represents a quantitative trait in human plasma associated
with atherothrombotic disease. Large variation in the distribution of Lp (a) concentrations …

Lipoprotein (a) in childhood: relation with other atherosclerosis risk factors and family history of atherosclerosis

S Bailleul, R Couderc, C Rossignol… - Clinical …, 1995 - academic.oup.com
The relation between lipoprotein (a)[Lp (a)], apolipoprotein (apo) E phenotypes, cholesterol,
triglycerides, apo AI, apo B, and a family history of atherosclerosis or risk factors was studied …

Lipoprotein (a) in women twins: heritability and relationship to apolipoprotein (a) phenotypes.

MA Austin, C Sandholzer, JV Selby… - American journal of …, 1992 - ncbi.nlm.nih.gov
Lp (a) is a unique lipoprotein consisting of an LDL-like particle and a characteristic protein,
apo (a). Increased levels of Lp (a) constitute a risk factor for coronary heart disease …

Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus.

CA DeMeester, X Bu, RJ Gray, AJ Lusis… - American journal of …, 1995 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)(Lp [a]) is a cholesterol-rich lipoprotein resembling LDL but also
containing a large polypeptide designated apolipoprotein (a)(apo [a]). Its levels are highly …

Segregation analysis of plasma lipoprotein (a) levels in pedigrees with molecularly defined familial hypercholesterolemia

Y Friedlander, E Leitersdorf - Genetic epidemiology, 1995 - Wiley Online Library
The role of genetic and environmental factors in determining the variability in plasma
lipoprotein (a)[Lp (a)] levels was investigated in 220 members of 14 families with familial …

Potential environmental effects on adult lipoprotein (a) levels: results from Swedish twins

Y Hong, GH Dahlén, N Pedersen, DA Heller… - Atherosclerosis, 1995 - Elsevier
Two hundred and ninety four pairs of Swedish twins reared apart and twins reared together
were used to evaluate the importance of genetic and environmental influences on …

Lp (a) concentration and apo (a) isoform size. Relation to the presence of coronary artery disease in familial hypercholesterolemia.

JF Bowden, PH Pritchard, JS Hill… - … and Thrombosis: A …, 1994 - Am Heart Assoc
We studied the relation between the concentration of lipoprotein (a)[Lp (a)] in plasma,
apolipoprotein (a)[apo (a)] phenotype, and the clinical expression of coronary artery disease …

Genetics and metabolism of lipoprotein (a) and their clinical implications (Part 1).

H Dieplinger, F Kronenberg - Wiener Klinische Wochenschrift, 1999 - europepmc.org
The human plasma lipoprotein Lp (a) has gained considerable clinical interest as a
genetically determined risk factor for atherosclerotic vascular diseases. Numerous (including …

Lp (a) lipoprotein is a major risk factor for cardiovascular disease: pathogenic mechanisms and clinical significance

GH Dahlén, H Stenlund - Clinical genetics, 1997 - Wiley Online Library
The results of two previous and two recent studies of middle‐aged males and females are
presented to exemplify the clinical importance of lipoprotein (a)(Lp (a)) as a risk factor for …