Inhaled silver nanoparticles induce pulmonary oxidative injury and inflammation: Differential effects between rat strains

J Seiffert, F Hussain, C Guo, Y Chang… - European …, 2014 - Eur Respiratory Soc
Introduction: Silver nanoparticles (AgNP) have been reported to induce pulmonary
inflammation and altered breathing rates in rodents however the mechanisms are poorly …

Pulmonary toxicity of instilled silver nanoparticles: influence of size, coating and rat strain

J Seiffert, F Hussain, C Wiegman, F Li, L Bey, W Baker… - PloS one, 2015 - journals.plos.org
Particle size and surface chemistry are potential determinants of silver nanoparticle (AgNP)
respiratory toxicity that may also depend on the lung inflammatory state. We compared the …

Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague–Dawley rats

J Seiffert, A Buckley, B Leo, NG Martin, J Zhu, R Dai… - Respiratory …, 2016 - Springer
Background The increasing use of silver nanoparticles (AgNPs) in consumer products is
concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) …

Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice

Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar - NanoImpact, 2021 - Elsevier
Silver nanoparticles (AgNPs) are the most commonly used nanoparticles (NPs) owing to
their anti-microbial properties, and the pulmonary system provides a major portal of entry for …

Aerosolized silver nanoparticles in the rat lung and pulmonary responses over time

RM Silva, DS Anderson, J Peake… - Toxicologic …, 2016 - journals.sagepub.com
Silver nanoparticle (Ag NP) production methods are being developed and refined to
produce more uniform Ag NPs through chemical reactions involving silver salt solutions …

Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

HM Braakhuis, I Gosens, P Krystek, JAF Boere… - Particle and fibre …, 2014 - Springer
Background Although silver nanoparticles are currently used in more than 400 consumer
products, it is not clear to what extent they induce adverse effects after inhalation during …

Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study

HM Braakhuis, FR Cassee, PHB Fokkens… - …, 2016 - Taylor & Francis
A number of studies have shown that induction of pulmonary toxicity by nanoparticles of the
same chemical composition depends on particle size, which is likely in part due to …

Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages

Y Arai, T Miyayama, S Hirano - Toxicology, 2015 - Elsevier
The health effects of silver nanoparticles (AgNPs) have not been well investigated, despite
AgNPs now being widely used in consumer products. We investigated the metabolic …

Nanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation model

LV Stebounova, A Adamcakova-Dodd, JS Kim… - Particle and fibre …, 2011 - Springer
Background There is increasing interest in the environmental and health consequences of
silver nanoparticles as the use of this material becomes widespread. Although human …

Pro-inflammatory versus immunomodulatory effects of silver nanoparticles in the lung: the critical role of dose, size and surface modification

F Alessandrini, A Vennemann, S Gschwendtner… - Nanomaterials, 2017 - mdpi.com
The growing use of silver nanoparticles (Ag-NPs) in consumer products raises concerns
about their toxicological potential. The purpose of the study was to investigate the size-and …