Melatonin is an indolamine synthesized and secreted by the pineal gland along with other
extrapineal sources including immune system cells, the brain, skin and the gastrointestinal …

Literature data indicate a significant immunoregulatory role of melatonin. Melatonin exerts
an effect directly affecting leucocytes bearing specific melatonin receptors or indirectly by …

Melatonin is mainly produced in the mammalian pineal gland during the dark phase. Its
secretion from the pineal gland has been classically associated with circadian and circanual …

Melatonin is a neurohormone produced by the pineal gland that regulates sleep and
circadian functions. Melatonin also regulates inflammatory and immune processes acting as …

Abstract N-acetyl-5-methoxy-tryptamine (melatonin) is a natural substance produced both by
plants, as a secondary metabolite, and animals, by the pineal gland and other tissues. In …

This review summarizes the present knowledge on melatonin in several areas on
physiology and discusses various prospects of its clinical utilization. Ever increasing …

Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

Melatonin is a hormone produced by the pineal gland. In addition to its hormonal effect, it
has strong antioxidant properties. Melatonin is probably best known for its ability to control …

Background: Melatonin is a molecule with numerous properties applicable to the treatment
of neurological diseases. Among these properties are the following: potent scavenger of …

Melatonin is a ubiquitous natural neurotransmitter-like compound produced primarily by the
pineal gland. This agent is involved in numerous aspects of the biological and physiologic …