Progesterone is an ovarian steroid hormone that is essential for normal breast development
during puberty and in preparation for lactation. The actions of progesterone are primarily …

Progesterone is an ovarian steroid hormone that is essential for normal breast development
during puberty and in preparation for lactation and breastfeeding. The actions of …

Progesterone and progesterone receptors (PR) have a storied albeit controversial history in
breast cancers. As endocrine therapies for breast cancer progressed through the twentieth …

Understanding the biology of the breast and how ovarian hormones impinge on it is key to
rational new approaches in breast cancer prevention and therapy. Because of the success …

In light of recent clinical trials, the debate concerning the risks and benefits of progestin-
based postmenopausal hormone replacement therapy (HRT) has reached a renewed level …

Synthetic progestogens (progestins) have been linked to increased breast cancer risk;
however, the role of endogenous progesterone in breast physiology and carcinogenesis is …

Progesterone and estradiol, and their nuclear receptors, play essential roles in the
physiology of the reproductive tract, the mammary gland and the nervous system. Estrogens …

Progesterone receptors (PR) are useful prognostic indicators of breast cancers likely to
respond to anti-estrogen receptor (ER) therapies. However, the role of progesterone …

Progesterone receptors (PR) play a pivotal role in many female reproductive tissues such as
the uterus, the ovary, and the mammary gland (MG). Moreover, PR play a key role in breast …

Progesterone is considered as the pregnancy hormone and acts on many different target
tissues. Progesterone receptor (PR) signaling is important for normal development and the …