[HTML][HTML] Vitamin E family: Role in the pathogenesis and treatment of Alzheimer's disease

V Boccardi, M Baroni, F Mangialasche… - Alzheimer's & Dementia …, 2016 - Elsevier
Introduction Vitamin E family, composed by tocopherols and tocotrienols, is a group of
compounds with neuroprotective properties. The exact role in the pathogenesis and the …

Role of vitamin E in the treatment of Alzheimer's disease: Evidence from animal models

A Gugliandolo, P Bramanti, E Mazzon - International Journal of Molecular …, 2017 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder representing the major cause of
dementia. It is characterized by memory loss, and cognitive and behavioral decline. In …

Vitamin E and Alzheimer's disease: what do we know so far?

D Browne, B McGuinness, JV Woodside… - … interventions in aging, 2019 - Taylor & Francis
Vitamin E has been proposed as a potential clinical intervention for Alzheimer's disease
(AD) given the plausibility of its various biological functions in influencing the …

Tocopherol (vitamin E) in Alzheimer's disease and other neurodegenerative disorders

K Berman, H Brodaty - CNS drugs, 2004 - Springer
In this article, we review the evidence that tocopherol (vitamin E) may have a role to play in
the prevention and treatment of Alzheimer's disease and other neurological diseases. The …

Effects of vitamin E on cognitive performance during ageing and in Alzheimer's disease

G La Fata, P Weber, MH Mohajeri - Nutrients, 2014 - mdpi.com
Vitamin E is an important antioxidant that primarily protects cells from damage associated
with oxidative stress caused by free radicals. The brain is highly susceptible to oxidative …

[HTML][HTML] Vitamin E: Curse or benefit in Alzheimer's disease? A systematic investigation of the impact of α-, γ-and δ-tocopherol on Aβ generation and degradation in …

MOW Grimm, CP Stahlmann, J Mett… - The Journal of nutrition …, 2015 - Elsevier
Objectives The E vitamins are a class of lipophilic compounds including tocopherols, which
have high antioxidative properties. Because of the elevated lipid peroxidation and increased …

High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age

F Mangialasche, M Kivipelto, P Mecocci… - Journal of …, 2010 - content.iospress.com
In this study we investigated the association between plasma levels of eight forms of vitamin
E and incidence of Alzheimer's disease (AD) among oldest-old individuals in a population …

A meta-analysis of peripheral tocopherol levels in age-related cognitive decline and Alzheimer's disease

S Ashley, S Bradburn, C Murgatroyd - Nutritional neuroscience, 2021 - Taylor & Francis
Objectives: Findings from observational studies and clinical trials on the associations
between vitamin E and dementia remain controversial. Here we conducted a meta-analysis …

Vitamin E forms in Alzheimer's disease: a review of controversial and clinical experiences

OB Usoro, SA Mousa - Critical reviews in food science and nutrition, 2010 - Taylor & Francis
Vitamin E is a collective term for eight naturally occurring compounds, four tocopherols
(alpha-, beta-, gamma-, and delta-) and four tocotrienols (alpha-, beta-, gamma-, and delta-) …

Tocopherols and tocotrienols plasma levels are associated with cognitive impairment

F Mangialasche, W Xu, M Kivipelto, E Costanzi… - Neurobiology of …, 2012 - Elsevier
Vitamin E includes 8 natural compounds (4 tocopherols, 4 tocotrienols) with potential
neuroprotective activity. α-Tocopherol has mainly been investigated in relation to cognitive …