Immunogenicity of three doses of bivalent, trivalent, or type 1 monovalent oral poliovirus vaccines with a 2 week interval between doses in Bangladesh: an open-label …

CF Estívariz, A Anand, HE Gary, M Rahman… - The Lancet Infectious …, 2015 - thelancet.com
Background The provision of several doses of monovalent type 1 oral poliovirus vaccine
(mOPV1) and bivalent OPV1 and 3 (bOPV) vaccines through campaigns is essential to stop …

Immunogenicity and effectiveness of routine immunization with 1 or 2 doses of inactivated poliovirus vaccine: systematic review and meta-analysis

NC Grassly - The Journal of infectious diseases, 2014 - academic.oup.com
Abstract Background. The World Health Organization has recommended that all 124
countries currently using only oral poliovirus vaccine (OPV) introduce at least 1 dose of …

Safety and immunogenicity of shorter interval schedules of the novel oral poliovirus vaccine type 2 in infants: a phase 3, randomised, controlled, non-inferiority study in …

LR Mejía, LP Méndez, AS Bandyopadhyay… - The Lancet Infectious …, 2024 - thelancet.com
Background The novel oral poliovirus vaccine type 2 (nOPV2) is now authorised by a WHO
emergency use listing and widely distributed to interrupt outbreaks of circulating vaccine …

Oral and inactivated poliovirus vaccines in the newborn: a review

FJ Mateen, RT Shinohara, RW Sutter - Vaccine, 2013 - Elsevier
BACKGROUND: Oral poliovirus vaccine (OPV) remains the vaccine-of-choice for routine
immunization and supplemental immunization activities (SIAs) to eradicate poliomyelitis …

Combined immunization of infants with oral and inactivated poliovirus vaccines: results of a randomized trial in The Gambia, Oman, and Thailand

WHO Collaborative Study Group on Oral … - The Journal of …, 1997 - academic.oup.com
To assess an immunization schedule combining oral (OPV) and inactivated poliovirus
vaccines (IPV), a clinical trial was conducted in The Gambia, Oman, and Thailand. Children …

Intestinal immune responses to type 2 oral polio vaccine (OPV) challenge in infants previously immunized with bivalent OPV and either high-dose or standard …

EB Brickley, CB Strauch… - The Journal of …, 2018 - academic.oup.com
Background The impact of inactivated polio vaccines (IPVs) on intestinal mucosal immune
responses to live poliovirus is poorly understood. Methods In a 2014 phase 2 clinical trial …

Serologic response to inactivated poliovirus vaccine: a randomized clinical trial comparing 2 vaccination schedules in Puerto Rico

GH Dayan, M Thorley, Y Yamamura… - The Journal of …, 2007 - academic.oup.com
Abstract Background The World Health Organization (WHO) recommends the
discontinuation of oral poliovirus vaccine after eradication of wild poliovirus. Studies …

Vaccine schedules and the effect on humoral and intestinal immunity against poliovirus: a systematic review and network meta-analysis

GR Macklin, NC Grassly, RW Sutter, O Mach… - The Lancet Infectious …, 2019 - thelancet.com
Background The eradication of wild and vaccine-derived poliovirus requires the global
withdrawal of oral poliovirus vaccines (OPVs) and replacement with inactivated poliovirus …

Immunogenicity of novel oral poliovirus vaccine type 2 administered concomitantly with bivalent oral poliovirus vaccine: an open-label, non-inferiority, randomised …

AL Wilkinson, K Zaman, M Hoque… - The Lancet Infectious …, 2023 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) was developed by modifying the
Sabin strain to increase genetic stability and reduce risk of seeding new circulating vaccine …

Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised …

J John, S Giri, AS Karthikeyan, M Iturriza-Gomara… - The Lancet, 2014 - thelancet.com
Background Intestinal immunity induced by oral poliovirus vaccine (OPV) is imperfect and
wanes with time, permitting transmission of infection by immunised children. Inactivated …