Background In 1988, the World Health Assembly resolved to eradicate poliomyelitis.
Although substantial progress toward this goal has been made, eradication remains elusive …

In April 2016, all 155 oral poliovirus vaccine (OPV)–using countries and territories in the
world discontinued use of Sabin poliovirus type 2 by switching from trivalent OPV (tOPV) to …

After the 2016 synchronized switch from trivalent oral poliovirus vaccine (OPV)(types 1, 2,
and 3) to bivalent OPV (types 1 and 3), transmission of type 2 circulating VDPVs (cVDPVs) …

The relative immunity induced by sequential administration of inactivated poliovirus vaccine
(IPV) produced in human diploid cells and live attenuated oral poliovirus vaccine (OPV) was …

Following global withdrawal of oral polio vaccine type 2 (OPV2) from national immunization
programmes in 2016, a confirmed type 2 event will be considered a public health …

Background The development of a Sabin strain–based inactivated poliovirus vaccine (Sabin-
IPV) is imperative to protecting against vaccine-associated paralytic poliomyelitis in …

Background Outbreaks of circulating vaccine derived polioviruses type 2 (cVDPV2) remain a
risk to poliovirus eradication in an era without live poliovirus vaccine containing type 2 in …

A controlled study was conducted in Karachi, Pakistan to compare humoral and mucosal
immune responses against polioviruses in infants who received oral poliovirus vaccine …

Inactivated poliovirus vaccine (IPV) may be used in mass vaccination campaigns during the
final stages of polio eradication. It is also likely to be adopted by many countries following …

Since 1997 when the American Academy of Pediatrics (AAP) issued revised guidelines for
the prevention of poliomyelitis, substantial progress in global eradication of poliomyelitis has …