The bacterial cell wall is a complex polymeric structure with essential roles in defence,
survival and pathogenesis. Common to both Gram-positive and Gram-negative bacteria is …

Bacteria account for 1000-fold more biomass than humans. They vary widely in shape and
size. The morphological diversity of bacteria is due largely to the different peptidoglycan …

Highlights•Lipid-linked steps of peptidoglycan assembly are high-value targets for drug
discovery.•Wall teichoic acid synthetic enzymes are a new class of antibacterial and/or …

The peptidoglycan is the key structural component of the bacterial cell wall that rests outside
the cytoplasmic membrane and provides bacterial cells with physical strength and shape. It …

The major constituent of bacterial cell walls is peptidoglycan, which, in its crosslinked form,
is a polymer of considerable complexity that encases the entire bacterium. A functional cell …

The bacterial cell wall is essential for survival, and proteins that participate in its biosynthesis
have been the targets of antibiotic development efforts for decades. The biosynthesis of its …

The peptidoglycan cell wall is a unique macromolecular structure in bacteria that defines
their shape and confers protection from the surrounding environment. Decades of research …

The cell wall imparts structural strength and shape to bacteria. It is made up of polymeric
glycan chains with peptide branches that are cross-linked to form the cell wall. The cross …

Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …

The peptidoglycan biosynthetic pathway is a critical process in the bacterial cell and is
exploited as a target for the design of antibiotics. This pathway culminates in the production …