Aporphine alkaloids embedded in 4 H-dibenzo [de, g] quinoline four-ring structures belong
to one of the largest subclasses of isoquinoline alkaloids. Aporphine is a privileged scaffold …

The aporphine alkaloids are known to have affinities as the dopaminergic, adrenergic and
serotonergic receptor system. Hence the aporphine template can be considered as a …

Aporphine compounds constitute a class of substances with important pharmacological
properties, including anticancer, antiviral, anti‐HIV, anti‐inflammatory, and leishmanicidal …

A series of new aporphine analogues (aporlogues) were prepared from appropriate
aporphine precursors and arylpiperazines using the Click reaction protocol. These …

Aporphine alkaloids constitute one of the largest groups of isoquinolines, with more than
500 structures reported to date. Structures of these alkaloids include aporphines …

The synthesis of 4 H-thiochromene derivatives of apomorphines, a novel class of
isoquinoline alkaloid-related compounds, has been achieved by different O-dealkylation …

The aporphine alkaloids constitute the second-largest group of isoquinoline alkaloids.
Nevertheless, only a relatively small number of natural aporphines and their derivatives …

A series of apomorphine ((−)-1, APO)-derived analogues ((±)-3,(−)-4-(−)-6) were designed
and synthesized by hybridizing APO with a privileged 2-aminothiazole functionality which …

Background Cancer is the most common cause of death and is still a serious public health
problem. Alkaloids, a class of bioactive compounds widely diffused in plants, especially …

7-Oxygenated aporphines 1–6 possessing anti-configurations have previously been
reported. In order to explore their bioactivities, a synthesis was established by utilizing a …