Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression

C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

[HTML][HTML] CircHIPK3: a promising cancer-related circular RNA

Y Zhang, Q Liu, Q Liao - American Journal of Translational …, 2020 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a special type of endogenous noncoding RNAs (ncRNAs), and
are characterized by a covalently closed loop structure without a 5'cap and poly-adenylated …

The circular RNA HIPK3 (circHIPK3) and its regulation in cancer progression

Y Xie, X Yuan, W Zhou, AA Kosiba, H Shi, J Gu, Z Qin - Life sciences, 2020 - Elsevier
Circular RNAs (circRNAs) are a class of covalently closed continuous loops of single-
stranded RNA molecules, and broadly expressed in the cytoplasm of eukaryotic cells …

The emerging role of circRNAs and their clinical significance in human cancers

L Qian, S Yu, Z Chen, Z Meng, S Huang… - Biochimica et Biophysica …, 2018 - Elsevier
Circular RNA (circRNA), a recently discovered subclass of non-coding RNAs (ncRNAs),
forms a covalently closed loop with neither a 5′ cap structure nor a 3′ polyadenylated tail …

Circular RNAs as biomarkers and therapeutic targets in cancer

A Beilerli, I Gareev, O Beylerli, G Yang, V Pavlov… - Seminars in cancer …, 2022 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed non-coding RNA molecules
(ncRNAs), which are formed as a result of reverse splicing of mRNAs. Despite their relative …

Circular RNAs: emerging cancer biomarkers and targets

Y Zhang, W Liang, P Zhang, J Chen, H Qian… - Journal of Experimental …, 2017 - Springer
CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are
abundant in eukaryotic transcripts and show certain levels of tissue and cell specificity …

Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …

Circ-IGF1R has pro-proliferative and anti-apoptotic effects in HCC by activating the PI3K/AKT pathway

H Fu, X Lin, Y Zhu, X Lan, Y Kuang, Y Wang, Z Ke… - Gene, 2019 - Elsevier
Circular RNAs (circRNAs), a novel class of widespread and diverse endogenous RNAs,
have been identified as critical regulators of various cancers, including hepatocellular …

CircRNAs and their regulatory roles in cancers

M Tao, M Zheng, Y Xu, S Ma, W Zhang, S Ju - Molecular Medicine, 2021 - Springer
Circular RNAs (circRNAs), a novel type of non-coding RNAs (ncRNAs), have a covalently
closed circular structure resulting from pre-mRNA back splicing via spliceosome and …

[HTML][HTML] Circular RNAs: regulators of cancer-related signaling pathways and potential diagnostic biomarkers for human cancers

Z Yang, L Xie, L Han, X Qu, Y Yang, Y Zhang, Z He… - Theranostics, 2017 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are newly discovered endogenous non-coding RNAs featuring
structural stability, high abundance, and tissue-specific expression. CircRNAs are prevalent …