[HTML][HTML] Recombinant human ACE2: potential therapeutics of SARS-CoV-2 infection and its complication

X Pang, Y Cui, Y Zhu - Acta Pharmacologica Sinica, 2020 - nature.com
Dear Editor, Since December 2019, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has caused a pneumonia outbreak in Wuhan city, China, followed by global …

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

D Batlle, J Wysocki, K Satchell - Clinical science, 2020 - portlandpress.com
A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of
severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019 …

Interaction of SARS-CoV-2 and other coronavirus with ACE (angiotensin-converting enzyme)-2 as their main receptor: therapeutic implications

AM Davidson, J Wysocki, D Batlle - Hypertension, 2020 - Am Heart Assoc
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 originated from Wuhan,
China, in December 2019 and rapidly spread to other areas worldwide. Since then …

[HTML][HTML] Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator

J Bian, Z Li - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) outbreak is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 …

[HTML][HTML] Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID19

TM Abd El-Aziz, A Al-Sabi, JD Stockand - Signal Transduction and …, 2020 - nature.com
A recent study by Zoufaly et al. published in The Lancet Respiratory Medicine describes
encouraging data from the first severe COVID-19 patient successfully treated with human …

[HTML][HTML] Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

W Ni, X Yang, D Yang, J Bao, R Li, Y Xiao, C Hou… - Critical Care, 2020 - Springer
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global …

[HTML][HTML] ACE2 Shedding and the Role in COVID-19

J Wang, H Zhao, Y An - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Angiotensin converting enzyme 2 (ACE2), a transmembrane glycoprotein, is an important
part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the …

Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2

M Gheblawi, K Wang, A Viveiros, Q Nguyen… - Circulation …, 2020 - Am Heart Assoc
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …

[HTML][HTML] Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection

L Guo, W Bi, X Wang, W Xu, R Yan, Y Zhang, K Zhao… - Cell Research, 2021 - nature.com
Dear Editor, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has resulted in a severe global pandemic. Following …

Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection

MW Zhuang, Y Cheng, J Zhang… - Journal of medical …, 2020 - Wiley Online Library
The ongoing outbreak of a new coronavirus (2019‐nCoV, or severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …