[HTML][HTML] Novel biomarkers for neoplastic progression from ulcerative colitis to colorectal cancer: a systems biology approach

M Shahnazari, S Afshar, MH Emami, R Amini… - Scientific Reports, 2023 - nature.com
In recent studies, the void of evaluation and in-depth understanding of unknown clinically
relevant potential molecular biomarkers involved in colorectal cancer (CRC) from the …

[HTML][HTML] An integrative transcriptome analysis reveals potential predictive, prognostic biomarkers and therapeutic targets in colorectal cancer

P Samadi, M Soleimani, F Nouri, F Rahbarizadeh… - BMC cancer, 2022 - Springer
Background A deep understanding of potential molecular biomarkers and therapeutic
targets related to the progression of colorectal cancer (CRC) from early stages to metastasis …

[HTML][HTML] Identification of hub genes and pathways in colitis-associated colon cancer by integrated bioinformatic analysis

Y Huang, X Zhang, PengWang, Y Li, J Yao - BMC Genomic Data, 2022 - Springer
Background Colitis-associated colon cancer (CAC) patients have a younger age of onset,
more multiple lesions and invasive tumors than sporadic colon cancer patients. Early …

[HTML][HTML] Analysis of genes involved in ulcerative colitis activity and tumorigenesis through systematic mining of gene co-expression networks

W Shi, R Zou, M Yang, L Mai, J Ren, J Wen… - Frontiers in …, 2019 - frontiersin.org
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disorder of the colon,
characterized by continuous mucosal inflammation. Recently, some studies have …

[HTML][HTML] Establishment of a colorectal cancer-related microrna-mrna regulatory network by microarray and bioinformatics

D Jiang, X Xie, Z Lu, L Liu, Y Qu, S Wu, Y Li, G Li… - Frontiers in …, 2020 - frontiersin.org
Colorectal cancer (CRC) is one of the most malignant cancers with high morbidity and
mortality. MicroRNAs (miRNAs) are small non-coding RNAs that affect biological processes …

[HTML][HTML] Integrated whole transcriptome and small RNA analysis revealed multiple regulatory networks in colorectal cancer

H Shaath, SM Toor, MA Nada, E Elkord, NM Alajez - Scientific Reports, 2021 - nature.com
Colorectal cancer (CRC) remains a global disease burden and a leading cause of cancer
related deaths worldwide. The identification of aberrantly expressed messenger RNA …

Identification of key regulators associated with colon cancer prognosis and pathogenesis

N Toolabi, FS Daliri, A Mokhlesi… - Journal of cell …, 2022 - Wiley Online Library
Colon cancer (CC) is the fourth deadliest cancer in the world. New insights into
prognostication might be helpful to define the optimal adjuvant treatments for patients in …

Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis

X Zhou, X Huang, S Liang, S Tang, S Wu… - OncoTargets and …, 2018 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the fourth most common cause of cancer-related
mortality worldwide. The tumor, node, metastasis (TNM) stage remains the standard for CRC …

[HTML][HTML] Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis

Y Li, M Tang, FJ Zhang, Y Huang, J Zhang, J Li… - Hereditas, 2022 - Springer
Background Ulcerative colitis (UC) refers to an intractable intestinal inflammatory disease. Its
increasing incidence rate imposes a huge burden on patients and society. The UC etiology …

[HTML][HTML] Identification of differentially expressed genes and miRNAs for ulcerative colitis using bioinformatics analysis

W Hu, T Fang, X Chen - Frontiers in Genetics, 2022 - frontiersin.org
Introduction: Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine whose
cause and underlying mechanisms are not fully understood. The aim of this study was to use …