Neutrophils are well known for their role in infection and inflammatory disease and are first
responders at sites of infection or injury. Platelets have an established role in hemostasis …

Platelets are essential for primary hemostasis, but they also play an important pro-
inflammatory role. Platelets normally circulate in a quiescent state. Upon activation, platelets …

Platelets primarily mediate hemostasis and thrombosis, whereas leukocytes are responsible
for immune responses. Since platelets interact with leukocytes at the site of vascular injury …

There is now a large body of evidence that platelets are central actors of inflammatory
reactions. Indeed, platelets play a significant role in a variety of inflammatory diseases …

Evidence indicates that complex interactions occur between platelets and neutrophils.
Mediators released by activated platelets may act as stimuli for neutrophils, but platelets may …

Atherothrombosis is a frequent cause of cardiovascular mortality. It is mostly triggered by
plaque rupture and exposure of the thrombogenic subendothelial matrix, which initiates …

Beyond their traditional role in haemostasis and thrombosis, platelets are increasingly
recognised as immune modulatory cells. Activated platelets and platelet-derived …

Neutrophils and platelets are among the most abundant cell types in peripheral blood and
characterized by high plasticity and a readily available reservoir of surface proteins and …

Platelets are the main players in thrombosis and hemostasis; however they also play
important roles during inflammation and infection. Through their surface receptors, platelets …

Systemic inflammatory responses are associated with high morbidity and mortality and
represent a diverse and clinically challenging group of diseases. Platelets are increasingly …