Regulation and tumor‐suppressive function of the miR‐379/miR‐656 (C14MC) cluster in cervical cancer

S Srinath, PV Jishnu, VK Varghese, V Shukla… - Molecular …, 2024 - Wiley Online Library
Cervical cancer (CC) is a key contributor to cancer‐related mortality in several countries.
The identification of molecular markers and the underlying mechanism may help improve …

Amplification and up-regulation of MIR30D was associated with disease progression of cervical squamous cell carcinomas

Y Zhou, Y Hao, Y Li, R Li, R Wu, S Wang, Z Fang - BMC cancer, 2017 - Springer
Background Cervical squamous cell carcinoma (CSCC) is the most frequent type among
cervical cancers. Although the altered miRNA miR-30d expression and the amplified …

Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer

J Xu, Y Li, F Wang, X Wang, B Cheng, F Ye, X Xie… - Oncogene, 2013 - nature.com
MicroRNAs (miRNAs) act as important gene regulators in human genomes and their
aberrant expression links to many malignancies. We previously identified a different …

Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers

SV Laddha, S Nayak, D Paul, R Reddy, C Sharma… - Biology direct, 2013 - Springer
Background MicroRNAs (miRNAs) are non-uniformly distributed in genomes and~ 30% of
the miRNAs in the human genome are clustered. In this study we have focused on the …

Integrated multiomics analysis of chromosome 19 miRNA cluster in bladder cancer

AP Ware, K Satyamoorthy, B Paul - Functional & Integrative Genomics, 2023 - Springer
With 46 microRNAs (miRNAs) embedded tandemly over a distance of~ 100 kb, chromosome
19 microRNA cluster (C19MC) is the largest miRNA cluster in the human genome. The …

N6-Methyladenosine Associated Silencing of miR-193b Promotes Cervical Cancer Aggressiveness by Targeting CCND1

C Huang, J Liang, S Lin, D Wang, Q Xie, Z Lin… - Frontiers in …, 2021 - frontiersin.org
Objective Cervical cancer is a frequently encountered gynecological malignancy as a major
contributor to cancer-related deaths in women. This study focuses on how miR-193b …

miR-10b downregulated by DNA methylation acts as a tumor suppressor in HPV-positive cervical cancer via targeting Tiam1

M Yu, Y Xu, L Pan, Y Feng, K Luo, Q Mu… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: microRNAs (miRNAs) are known to act as oncogenes or tumor
suppressors in diverse cancers. Although miR-10b is an oncogene implicated in many …

MicroRNA‑29a inhibits cell proliferation and arrests cell cycle by modulating p16 methylation in cervical cancer

A Wang, Q Xu, R Sha, T Bao, X Xi… - Oncology …, 2021 - spandidos-publications.com
Cervical cancer is the second most common gynecological malignancy. Accumulating
evidence has suggested that microRNAs (miRNAs) are involved in the occurrence and …

[HTML][HTML] miR-326 inhibits the cell proliferation and cancer stem cell-like property of cervical cancer in vitro and oncogenesis in vivo via targeting TCF4

J Zhang, H He, K Wang, Y Xie, Z Yang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Cervical cancer ranks as one of the most prevalent female malignancies
globally, and its treatment with new targets has been the focus of current research. The …

MiR-150 and miR-155 expression predicts survival of cervical cancer patients: A translational approach to novel prognostic biomarkers

JMO Santos, V Tavares, RM Gil da Costa… - Biomarkers, 2023 - Taylor & Francis
Introduction High-risk human papillomavirus (HPV) is the aetiological agent of cervical
cancer, which remains the fourth leading cause of cancer death in women worldwide. K14 …