The Plasmodium parasite has to cross various immunological barriers for successful
infection. Parasites have evolved mechanisms to evade host immune responses, which …

Elucidating the molecular mechanisms of the host-parasite interaction during red cell
invasion by Plasmodium is important for developing newer antimalarial therapeutics …

Human malarial infection occurs after an infectious Anopheles mosquito bites. Following the
initial liver‐stage infection, parasites transform into merozoites, infecting red blood cells …

The pathogenesis of cerebral malaria is biologically complex and involves multi-factorial
mechanisms such as microvascular congestion, immunopathology by the pro-inflammatory …

An effective vaccine to reduce malaria transmission is central to control and ultimately
achieve disease eradication. Recently, we demonstrated that antibodies targeting the …

Malaria transmission relies on parasite-mosquito midgut interaction. The interactive proteins
are hypothesized to be ideal targets to block malaria transmission to mosquitoes. We chose …

Plasmodium vivax, the most widespread human malaria parasite, and P. knowlesi, an
emerging Plasmodium that infects humans, are the phylogenetically closest malarial species …

During their development within the vertebrate host, Plasmodium parasites infect
hepatocytes and red blood cells. Within these cells, parasites are surrounded by a …

Malaria parasites actively remodel the infected red blood cell (irbc) by exporting proteins into
the host cell cytoplasm. The human parasite Plasmodium falciparum exports particularly …

The inability to acquire protective immunity against Plasmodia is the chief obstacle to
malaria control, and inadequate T-cell responses may facilitate persistent blood-stage …