Myotonic dystrophy is an autosomal dominant genetic disease of nucleotide expansion
resulting in neuromuscular disease with two distinct subtypes. There are significant systemic …

Myotonic dystrophy often presents with cardiac abnormalities, particularly conduction
defects, that factor into an increased risk of sudden cardiac death. Myotonic dystrophy has …

The association between systolic cardiac dysfunction and arrhythmia development in
patients with Duchenne muscular dystrophy (DMD) or Becker muscular dystrophy (BMD) is …

Hereditary muscular diseases commonly involve the heart. Cardiac manifestations
encompass a spectrum of phenotypes, including both cardiomyopathies and rhythm …

Background Myotonic dystrophy type 1 involves cardiac conduction disorders. Cardiac
conduction disease can cause fatal arrhythmias or sudden death in patients with myotonic …

AIMS: To estimate the degree of cardiac involvement regarding left ventricular ejection
fraction, conduction abnormalities, arrhythmia, risk of sudden cardiac death (SCD) and the …

Duchenne muscular dystrophy (DMD) is a clinically common X-linked recessive myopathy,
which is caused by mutation of the gene encoding dystrophin on chromosome Xp21. The …

Objectives Duchenne muscular dystrophy (DMD) is the most common and severe
dystrophinopathy. DMD carriers rarely present with clinical symptoms, but may suffer from …

Cardiac abnormalities occur in association with many of the neuromuscular disorders that
present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and …

Sudden cardiac death (SCD) risk assessment among patients with nonischemic
cardiomyopathy (NICM) has been has been less straightforward than for patients with …