Neisseria gonorrhoeae survives within and modulates apoptosis and inflammatory cytokine production of human macrophages

A Château, HS Seifert - Cellular microbiology, 2016 - Wiley Online Library
The human‐adapted organism Neisseria gonorrhoeae is the causative agent of gonorrhoea,
a sexually transmitted infection. It readily colonizes the genital, rectal and nasalpharyngeal …

[HTML][HTML] Neisseria gonorrhoeae host adaptation and pathogenesis

SJ Quillin, HS Seifert - Nature Reviews Microbiology, 2018 - nature.com
The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

[HTML][HTML] Commensal Neisseria species share immune suppressive mechanisms with Neisseria gonorrhoeae

W Zhu, MX Cardenas-Alvarez, J Tomberg, MB Little… - Plos one, 2023 - journals.plos.org
Neisseria gonorrhoeae is a highly adapted human sexually transmitted pathogen that can
cause symptomatic infections associated with localized inflammation as well as …

[HTML][HTML] Neisseria gonorrhoeae Suppresses Dendritic Cell-Induced, Antigen-Dependent CD4 T Cell Proliferation

W Zhu, MS Ventevogel, KJ Knilans, JE Anderson… - PloS one, 2012 - journals.plos.org
Neisseria gonorrhoeae is the second most common sexually transmitted bacterial pathogen
worldwide. Diseases associated with N. gonorrhoeae cause localized inflammation of the …

Defenses against Oxidative Stress in Neisseria gonorrhoeae: a System Tailored for a Challenging Environment

KL Seib, HJ Wu, SP Kidd, MA Apicella… - Microbiology and …, 2006 - Am Soc Microbiol
Neisseria gonorrhoeae is a host-adapted pathogen that colonizes primarily the human
genitourinary tract. This bacterium encounters reactive oxygen and reactive nitrogen species …

[HTML][HTML] The Pathobiology of Neisseria gonorrhoeae Lower Female Genital Tract Infection

JL Edwards, EK Butler - Frontiers in microbiology, 2011 - frontiersin.org
Infection and disease associated with Neisseria gonorrhoeae, the gonococcus, continue to
be a global health problem. Asymptomatic and subclinical gonococcal infections occur at a …

Neisseria gonorrhoeae Infection Protects Human Endocervical Epithelial Cells from Apoptosis via Expression of Host Antiapoptotic Proteins

SA Follows, J Murlidharan, P Massari… - Infection and …, 2009 - Am Soc Microbiol
Several microbial pathogens can modulate the host apoptotic response to infection, which
may contribute to immune evasion. Various studies have reported that infection with the …

Dinner date: Neisseria gonorrhoeae central carbon metabolism and pathogenesis

AD Potter, AK Criss - Emerging Topics in Life Sciences, 2023 - portlandpress.com
Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection gonorrhea,
is a human-adapted pathogen that does not productively infect other organisms. The …

[HTML][HTML] Human Immune Responses and the Natural History of Neisseria gonorrhoeae Infection

A Lovett, JA Duncan - Frontiers in immunology, 2019 - frontiersin.org
The intimate relationship between humans and Neisseria gonorrhoeae infections span
centuries, which is evidenced in case reports from studies dating back to the late 1700s and …

[HTML][HTML] Neisseria gonorrhoeae blocks epithelial exfoliation by nitric-oxide-mediated metabolic cross talk to promote colonization in mice

P Muenzner, CR Hauck - Cell host & microbe, 2020 - cell.com
Several pathogens suppress exfoliation, a key defense of epithelia against microbial
colonization. Common among these pathogens, exemplified by Neisseria gonorrhoeae, is …