Neisseria gonorrhoeae is evolving into a superbug with resistance to previously and
currently recommended antimicrobials for treatment of gonorrhea, which is a major public …

Neisseria gonorrhoeae (gonococcus) causes the human sexually transmitted disease
gonorrhea. Studying gonococcal pathogenesis and developing new vaccines and therapies …

Eighty percent of Neisseria gonorrhoeae strains and some Neisseria meningitidis strains
encode a 57-kb gonococcal genetic island (GGI). The GGI was horizontally acquired and is …

Neisseria gonorrhoeae is the causative agent of gonorrhea, a disease restricted to humans.
Complement forms a key arm of the innate immune system that combats gonococcal …

Neisseria gonorrhoeae infections are a serious global health problem. This organism has
developed disturbing levels of antibiotic resistance, resulting in the need for new …

Experimental infection of male volunteers with Neisseria gonorrhoeae is safe and
reproduces the clinical features of naturally acquired gonococcal urethritis. Human …

OxyR regulates the expression of the majority of H2O2 responses in Gram‐negative
organisms. In a previous study we reported the OxyR‐dependent derepression of catalase …

Gonorrhea is a highly prevalent disease resulting in significant morbidity worldwide, with an
estimated 106 cases reported annually. Neisseria gonorrhoeae, the causative agent of …

Neisseria gonorrhoeae and Neisseria meningitidis have become exquisitely adapted to life
within humans, their only natural host. Both species possess the ability to colonize human …

Background Neisseria gonorrhoeae (GC) is a Gram-negative pathogen that most commonly
infects mucosal surfaces, causing sexually transmitted urethritis in men and endocervicitis in …