Background Global concern over the rapid expansion of the Asian tiger mosquito, Aedes
albopictus, and its vector competence has highlighted an urgent need to improve currently …

Background Aedes aegypti is the principal vector of several important arboviruses. Among
the methods of vector control to limit transmission of disease are genetic strategies that …

Aedes albopictus is a major vector of arboviruses. Better understanding of its sex
determination is crucial for developing mosquito control tools, especially genetic sexing …

The initial signal that governs sex determination is highly variable among insects. A
homolog of Nix, the male-determining factor in Aedes aegypti, was previously found in the …

The mosquito family Culicidae is divided into 2 subfamilies named the Culicinae and
Anophelinae. Nix, the dominant male-determining factor, has only been found in the …

A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …

The preservation of a homomorphic sex-determining chromosome in some organisms
without transformation into a heteromorphic sex chromosome is a long-standing enigma in …

The understanding of the molecular mechanisms of sex differentiation in the mosquito
Anopheles gambiae could identify important candidate genes for inducing selective male …

Sexual reproduction is critical to the survival and evolution of many organisms including
mosquitoes. Sex determination in insects is often initiated by a fast-evolving primary signal …

Background More effective mosquito control strategies are urgently required due to the
increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the …