The metabolic switch and its regulation in cancer cells

ST Zhou, CH Huang, YQ Wei - Science China Life Sciences, 2010 - Springer
The primary features of cancer are maintained via intrinsically modified metabolic activity,
which is characterized by enhanced nutrient supply, energy production, and biosynthetic …

Metabolic tricks of cancer cells

K Hönigova, J Navratil, B Peltanova… - … et Biophysica Acta (BBA …, 2022 - Elsevier
One of the characteristics of cancer cells important for tumorigenesis is their metabolic
plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic …

[HTML][HTML] Cancer metabolism and intervention therapy

H Zhao, Y Li - Molecular Biomedicine, 2021 - Springer
Metabolic reprogramming with heterogeneity is a hallmark of cancer and is at the basis of
malignant behaviors. It supports the proliferation and metastasis of tumor cells according to …

Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression

Z Li, H Zhang - Cellular and molecular life sciences, 2016 - Springer
Metabolic reprogramming is widely observed during cancer development to confer cancer
cells the ability to survive and proliferate, even under the stressed, such as nutrient-limiting …

[HTML][HTML] Dysregulated metabolic enzymes and metabolic reprogramming in cancer cells

A Sreedhar, Y Zhao - Biomedical reports, 2018 - spandidos-publications.com
Tumor cells carry various genetic and metabolic alterations, which directly contribute to their
growth and malignancy. Links between metabolism and cancer are multifaceted. Metabolic …

The metabolic alterations of cancer cells

M Sciacovelli, E Gaude, M Hilvo, C Frezza - Methods in enzymology, 2014 - Elsevier
Cancer cells exhibit profound metabolic alterations, allowing them to fulfill the metabolic
needs that come with increased proliferation and additional facets of malignancy. Such a …

[HTML][HTML] Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies

LM Phan, SCJ Yeung, MH Lee - Cancer biology & medicine, 2014 - ncbi.nlm.nih.gov
Cancer cells are well documented to rewire their metabolism and energy production
networks to support and enable rapid proliferation, continuous growth, survival in harsh …

[HTML][HTML] Dysregulated metabolism in cancer

A Isa - Biomedical Research and Therapy, 2022 - biomedpress.org
Metabolism describes the cellular bioenergetic pathways that provide energy and
macromolecules for protein, lipid, and nucleic acid syntheses. In cancer, malignant cells …

Fundamentals of cancer metabolism

RJ DeBerardinis, NS Chandel - Science advances, 2016 - science.org
Tumors reprogram pathways of nutrient acquisition and metabolism to meet the
bioenergetic, biosynthetic, and redox demands of malignant cells. These reprogrammed …

Metabolic reprogramming in cancer: Mechanisms and therapeutics

S Nong, X Han, Y Xiang, Y Qian, Y Wei, T Zhang… - MedComm, 2023 - Wiley Online Library
Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …