There is increasing evidence that growth factors modulate folliculogenesis. However their
precise role in the processes of follicular growth, differentiation and atresia is still unknown …

Introduction I NSULIN-like growth factor-I (IGF-I) and its structural homologue, IGF-II, are low
molecular weight peptides that promote cellular mitosis and differentiation in a variety of …

In the ovary, insulin-like growth factors (IGFs) enhance both proliferation and differentiation
of follicular cells by potentiating gonadotropin's actions. The biological effects of IGFs are …

Contents The aim of the present paper is to make a comparative study of the expression of
the elements of the insulin‐like growth factor (IGF) system in different mammalian species …

The insulin-like growth factor (IGF) family plays an important role in follicle development,
dominant follicle growth and steroidogenesis, and follicular atresia. Insulin-like growth factor …

Context: Polycystic ovary syndrome (PCOS), the commonest cause of anovulatory infertility,
is characterized by disordered follicle development including increased activation and …

Ovarian follicular development is under the influence of gonadotrophins. The manner by
which gonadotrophins achieve their role in cell replication and hormone production is …

The insulin-like growth factor (IGF) system is an essential component of the intraovarian
mechanisms involved in the regulation of follicle growth and corpus luteum function …

The IGFs are believed to play an important role in the regulation of steroidogenesis and
follicular maturation in the human ovary. The activities of the IGFs are regulated by a family …

Objective: To review the available information regarding the roles of insulin‐like growth
factor (IGF)‐IGF binding protein (IGFBP) system in ovarian physiology. Design: Studies that …