Circadian clock proteins form an autoregulatory feedback loop that is central to the
endogenous generation and transmission of daily rhythms in behavior and physiology …

The molecular circadian clock regulates rhythmic transcription of thousands of genes
throughout the brain and body, providing transcriptional coordination of a broad range of …

Almost every physiological or behavioral process in mammals follows rhythmic patterns,
which depend mainly on a master circadian clock located in the hypothalamic …

Evidence from clinical and preclinical research provides an undeniable link between
disruptions in the circadian clock and the development of psychiatric diseases, including …

Determining the cause of psychiatric disorders is a goal of modern neuroscience, and will
hopefully lead to the discovery of treatments to either prevent or alleviate the suffering …

Mammalian physiology and behavior are regulated by an internal time-keeping system,
referred to as circadian rhythm. The circadian timing system has a hierarchical organization …

Circadian rhythms are generated by an endogenously organized timing system that drives
daily rhythms in behavior, physiology and metabolism. In mammals, the suprachiasmatic …

Circadian rhythms are daily rhythms that regulate many biological processes–from gene
transcription to behavior–and a disruption of these rhythms can lead to a myriad of health …

To anticipate and adapt to daily recurring events defined by the earth's rotation such as light-
dark and temperature cycles, most species have developed internal, so-called circadian …

Elucidation of the cellular and molecular mechanisms of the circadian clock, along with the
realization that these mechanisms are operative in both central and peripheral tissues, has …