Toll-like receptors (TLRs) play a crucial role in host defence and inflammation. Given that a
significant amount of evidence implicates TLRs in the pathogenesis of immune diseases …

Toll-like receptors (TLRs) play a crucial role in innate immune responses to infection.
Binding of agonists to TLRs promotes maturation of antigen presenting cells, such as …

Toll-like receptors (TLRs) are the pattern recognition receptors, which are activated by
foreign and host molecules in order to initiate the immune response. They play a crucial role …

Toll‐like receptors (TLRs) are germline‐encoded receptors that are central to innate and
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …

Toll‐like receptors (TLRs) play a fundamental role in recognizing infectious and noxious
agents as well as products of tissue damage. They are capable of initiating both protective …

Since the identification of the first Toll-like receptor (TLR) in humans in 1997, understanding
of the molecular basis for innate immunity has increased significantly. The TLR family and …

Roles for Toll-like receptors (TLRs) are emerging in conditions such as sepsis syndrome,
systemic lupus erythromatosis, rheumatoid arthritis and asthma, suggesting that the …

ABSTRACT Introduction: Pattern recognition receptors (PRRs) of the innate immune system
mediate and control the activation and progression of adaptive immunity. Toll-like receptors …

Introduction: The immune response is mediated via two parallel immune components, innate
and adaptive, whose effector functions are highly integrated and coordinated for the …

In the past few years there has been an increasing appreciation of the importance of Toll-like
receptors (TLRs), not just in immunity, but also in autoimmune diseases. TLRs were first …