Numerous clinical and animal studies show that hormone replacement therapy reduces the
risk of colon tumor formation. However, the majority of experiments have shown that …

Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

The characterization of estrogen receptor beta (ERβ) brought new insight into the
mechanisms underlying estrogen signaling. Estrogen induction of cell proliferation is a …

Estrogen receptors (ERα and ERβ) mediate opposite functions on cancer growth induced by
17β-estradiol (E2). E2 binding to ERα induces a cancer promoting response, whereas E2 …

Clinical evidence suggests that estradiol replacement therapy reduces colon cancer risk in
'post'menopausal women. In colon epithelial cells, the estrogen receptor β (ERβ) is the …

Worldwide, gastric cancer is one of the most common malignancies with high mortality.
Various aspects of the development and progression of gastric cancer continue to be …

We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human
colorectal tumour tissues and adjacent normal mucosa by reverse transcriptase and nested …

Estrogens play important roles in the development and progression of multiple tumor types.
Accumulating evidence points to the significance of estrogen action not only in tumors of …

In recent years, several lines of epidemiologic, clinical and experimental evidences have
been reported showing that estrogen hormones may be involved in malignant colorectal …

Estrogen receptor β (ERβ) is the predominant ER in the colorectal epithelium. Compared
with normal colon tissue, ERβ expression is reduced in colorectal cancer. Our hypothesis is …