The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …

Estrogen receptors (ERα and ERβ) are ligand-activated transcription factors that play
different roles in gene regulation and show both overlapping and specific tissue distribution …

Estrogens play essential roles in the progression of mammary and prostatic diseases. The
transcriptional effects of estrogens are transduced by two estrogen receptors, ERα and ERβ …

Our understanding of estrogen signaling has undergone a true paradigm shift over recent
years, following the discovery in 1995 of a second estrogen receptor, estrogen receptor β …

AIM: To determine the expression of estrogen receptor (ER) β in Chinese colorectal
carcinoma (CRC) patients. METHODS: ERβ expression in CRC was investigated by …

Estrogen-signaling pathways are implicated in the development of breast cancer and
prostate cancer. Various studies have focused on additional signaling pathways, mediated …

Gender differences in the incidence and behaviour of colon cancer suggest a hormonal
influence and epidemiological data suggest a protective effect for hormone replacement …

Knockout and expression studies suggest that estrogen receptor β (ERβ) plays a prominent
role in ovarian function and pathology. Moreover, ovarian cancers are characterized by high …

The estrogen receptor (ER) has functionality in selected ovarian cancer subtypes and
represents a potential target for therapy. The majority (> 80%) of high grade serous, low …

Recent studies have shown that estrogens promote the growth of lung cancer cells and may
potentially be responsible for increased susceptibility to lung cancer in women. These …