[HTML][HTML] The impact of obesity, adipose tissue, and tumor microenvironment on macrophage polarization and metastasis
O Habanjar, M Diab-Assaf, F Caldefie-Chezet, L Delort - Biology, 2022 - mdpi.com
Simple Summary The inflammatory adipose microenvironment in obesity plays a crucial role
in cancer development and metastases. By focusing on adipocytes and macrophages, as …
in cancer development and metastases. By focusing on adipocytes and macrophages, as …
[HTML][HTML] Adipocytes and macrophages interplay in the orchestration of tumor microenvironment: new implications in cancer progression
Inflammation has been known as one of the main keys to the establishment and progression
of cancers. Chronic low-grade inflammation is also a strategic condition that underlies the …
of cancers. Chronic low-grade inflammation is also a strategic condition that underlies the …
Adipose tissue macrophages: the inflammatory link between obesity and cancer?
M Wagner, ES Samdal Steinskog… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Obesity has increased dramatically over the last three decades. Thus,
epidemiological evidence linking obesity and cancer has ignited our interest in the …
epidemiological evidence linking obesity and cancer has ignited our interest in the …
[HTML][HTML] The adipocyte–macrophage relationship in cancer: A potential target for antioxidant therapy
Obesity has emerged as a major public health concern with a staggering 39% worldwide
prevalence as of 2021. Given the magnitude of the problem and considering its association …
prevalence as of 2021. Given the magnitude of the problem and considering its association …
[HTML][HTML] Obesity-induced changes in cancer cells and their microenvironment: Mechanisms and therapeutic perspectives to manage dysregulated lipid metabolism
M Lee-Rueckert, M Canyelles, M Tondo… - Seminars in cancer …, 2023 - Elsevier
Obesity has been closely related to cancer progression, recurrence, metastasis, and
treatment resistance. We aim to review recent progress in the knowledge on the obese …
treatment resistance. We aim to review recent progress in the knowledge on the obese …
Cancer as a matter of fat: the crosstalk between adipose tissue and tumors
Obesity has been linked to the increased risk and aggressiveness of many types of
carcinoma. A state of chronic inflammation in adipose tissue (AT), resulting in genotoxic …
carcinoma. A state of chronic inflammation in adipose tissue (AT), resulting in genotoxic …
Obesity programs macrophages to support cancer progression
Obesity induces multifactorial effects such as dyslipidemia, insulin resistance, and arterial
hypertension that influence the progression of many diseases. Obesity is associated with an …
hypertension that influence the progression of many diseases. Obesity is associated with an …
Cytokines, obesity, and cancer: new insights on mechanisms linking obesity to cancer risk and progression
CA Gilbert, JM Slingerland - Annual review of medicine, 2013 - annualreviews.org
Obesity is a problem of epidemic proportions in many developed nations. Increased body
mass index and obesity are associated with a significantly worse outcome for many cancers …
mass index and obesity are associated with a significantly worse outcome for many cancers …
[HTML][HTML] The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance
MN Duong, A Geneste, F Fallone, X Li, C Dumontet… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Growing evidence has raised the important roles of adipocytes as an active player in the
tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells …
tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells …
Emerging concepts linking obesity with the hallmarks of cancer
There is compelling epidemiological evidence linking obesity to many tumours; however, the
molecular mechanisms fuelling this association are not clearly understood. Emerging …
molecular mechanisms fuelling this association are not clearly understood. Emerging …
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