Neutrophil-derived cytokines involved in physiological and pathological angiogenesis

C Tecchio, MA Cassatella - Angiogenesis, Lymphangiogenesis and …, 2014 - karger.com
Increasing data from the literature point to a neutrophil-mediated role via cytokine production
in several aspects of mammalian biology, including angiogenesis. In such regard …

Neutrophils and angiogenesis: potential initiators of the angiogenic cascade

R Benelli, A Albini, D Noonan - Chemical immunology, 2003 - books.google.com
Mature neutrophils are able to regulate several aspects of the immune response; their
influence extends beyond innate immunity, as they can modify lymphocyte maturation and …

The multitasking neutrophils and their involvement in angiogenesis

C Seignez, M Phillipson - Current opinion in hematology, 2017 - journals.lww.com
The multitasking neutrophils and their involvement in angiog... : Current Opinion in
Hematology The multitasking neutrophils and their involvement in angiogenesis : Current …

Human neutrophils promote angiogenesis by a paracrine feedforward mechanism involving endothelial interleukin-8

R Schruefer, N Lutze… - American Journal of …, 2005 - journals.physiology.org
Neovascularization by sprouting angiogenesis is critical for inflammation-mediated tissue
remodeling and wound healing. We report here that human polymorphonuclear neutrophils …

Neutrophils as effectors of vascular inflammation

D Gómez‐Moreno, JM Adrover… - European journal of …, 2018 - Wiley Online Library
Vascular inflammation underlies most forms of cardiovascular disease, which remains a
prevalent cause of death among the global population. Advances in the biology of …

Angiogenic activity of bFGF and VEGF suppressed by proteolytic cleavage by neutrophil elastase

S Ai, XW Cheng, A Inoue, K Nakamura… - Biochemical and …, 2007 - Elsevier
Neutrophil elastase (NE), a serine protease released from the azurophil granules of
activated neutrophil, proteolytically cleaves multiple cytokines, and cell surface proteins. In …

The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of …

R Schruefer, S Sulyok, J Schymeinsky… - Journal of vascular …, 2005 - karger.com
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are
critically involved in inflammation-mediated angiogenesis which is important for wound …

Identification and characterization of VEGF-A–responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

S Massena, G Christoffersson… - Blood, The Journal …, 2015 - ashpublications.org
Vascular endothelial growth factor A (VEGF-A) is upregulated during hypoxia and is the
major regulator of angiogenesis. VEGF-A expression has also been found to recruit myeloid …

Neutrophil extracellular traps, angiogenesis and cancer

R Poto, L Cristinziano, L Modestino, A de Paulis… - Biomedicines, 2022 - mdpi.com
Human neutrophils, the most abundant circulating leukocytes, are fundamental components
of the host response against different pathogens. Until a few years ago, neutrophils received …

The good, the bad, and the ugly: neutrophils, angiogenesis, and cancer

I Ozel, I Duerig, M Domnich, S Lang, E Pylaeva… - Cancers, 2022 - mdpi.com
Simple Summary Tumor angiogenesis is one of the most critical steps in the progression of
cancer. Owing to its fundamental role in tumor growth and metastasis, tumor angiogenesis is …