Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils
S Loffredo, F Borriello, R Iannone, AL Ferrara… - Frontiers in …, 2017 - frontiersin.org
Secreted phospholipases A2 (sPLA2s) are extracellular enzymes that catalyze the release
of free fatty acids and lysophospholipids from membrane phospholipids and also bind to …
of free fatty acids and lysophospholipids from membrane phospholipids and also bind to …
Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis
J Kreuger, M Phillipson - Nature Reviews Drug Discovery, 2016 - nature.com
Regulation of vascular permeability, recruitment of leukocytes from blood to tissue and
angiogenesis are all processes that occur at the level of the microvasculature during both …
angiogenesis are all processes that occur at the level of the microvasculature during both …
Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D
KW Tan, SZ Chong, FHS Wong… - Blood, The Journal …, 2013 - ashpublications.org
Lymphangiogenesis is an important physiological response to inflammatory insult, acting to
limit inflammation. Macrophages, dendritic cells, and lymphocytes are known to drive …
limit inflammation. Macrophages, dendritic cells, and lymphocytes are known to drive …
[HTML][HTML] Fibroblast activation in vascular inflammation
A Enzerink, A Vaheri - Journal of Thrombosis and Haemostasis, 2011 - Elsevier
Vascular inflammation is implicated in both local and systemic inflammatory conditions.
Endothelial activation and leukocyte extravasation are key events in vascular inflammation …
Endothelial activation and leukocyte extravasation are key events in vascular inflammation …
Emerging mechanisms of neutrophil recruitment across endothelium
Neutrophils are the all-terrain vehicle of the innate immune system because of their ability to
gain entry into tissues and organs, and thus, play an essential role in host defense. Exactly …
gain entry into tissues and organs, and thus, play an essential role in host defense. Exactly …
The molecular basis of VEGFR-1 signal transduction pathways in primary human monocytes
V Tchaikovski, G Fellbrich… - … thrombosis, and vascular …, 2008 - Am Heart Assoc
Objective—Arteriogenesis, the growth of preexisting arterioles into functional arteries, is
dependent on the proper function of monocytes. Likewise, wound healing is monocyte …
dependent on the proper function of monocytes. Likewise, wound healing is monocyte …
Angiopoietin-1 induces migration of monocytes in a tie-2 and integrin-independent manner
Angiopoietin-1 (Ang-1) is an angiogenic growth factor that activates Tie-2 and integrins to
promote vessel wall remodeling. The recent finding of the potential proatherogenic effects of …
promote vessel wall remodeling. The recent finding of the potential proatherogenic effects of …
PGF2α, a prostanoid released by endothelial cells activated by hypoxia, is a chemoattractant candidate for neutrophil recruitment
T Arnould, R Thibaut-Vercruyssen, N Bouaziz… - The American journal of …, 2001 - Elsevier
Despite increasing evidence supporting the involvement of neutrophils in ischemic and
postischemic damages, the mechanisms underlying the early recruitment of these cells are …
postischemic damages, the mechanisms underlying the early recruitment of these cells are …
Interleukin‐1α (IL‐1α) promotes angiogenesis in vivo via VEGFR‐2 pathway by inducing inflammatory cell VEGF synthesis and secretion
During inflammation, functional changes occur in the vasculature, including extensive
endothelial cell mitotic activity and remodeling of capillaries. Interleukin‐1α.(IL‐1α) is a …
endothelial cell mitotic activity and remodeling of capillaries. Interleukin‐1α.(IL‐1α) is a …
Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation
P Dentelli, LD Sorbo, A Rosso, A Molinar… - The Journal of …, 1999 - journals.aai.org
Angiogenesis is a critical process for growth of new capillary blood vessels from preexisting
capillaries and postcapillary venules, both in physiological and pathological conditions …
capillaries and postcapillary venules, both in physiological and pathological conditions …