Loss of YAP protein in prostate cancer is associated with Gleason score increase
X Hu, Y Jia, J Yu, J Chen, Q Fu - Tumori Journal, 2015 - journals.sagepub.com
Aims and Background To investigate the expression of YAP protein by
immunohistochemistry in prostate cancer tissues and hyperplasia or normal prostate tissues …
immunohistochemistry in prostate cancer tissues and hyperplasia or normal prostate tissues …
[HTML][HTML] Yes-associated protein expression is correlated to the differentiation of prostate adenocarcinoma
Background Yes-associated protein (YAP) in the Hippo signaling pathway is a growth
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
[HTML][HTML] Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension
Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
YAP1 is involved in tumorigenic properties of prostate cancer cells
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells
X Sheng, WB Li, DL Wang… - Molecular …, 2015 - spandidos-publications.com
Yes-associated protein 65 (YAP65) has been implicated as an oncogene, and its expression
is increased in human cancer. Previous studies have demonstrated that alterations in YAP …
is increased in human cancer. Previous studies have demonstrated that alterations in YAP …
[HTML][HTML] YAP knockdown inhibits proliferation and induces apoptosis of human prostate cancer DU145 cells
X Jin, W Zhao, P Zhou, T Niu - Molecular medicine …, 2018 - spandidos-publications.com
The role of yes-associated protein (YAP) in human prostate cancer DU145 cells and its
underlying molecular mechanisms were explored in the present study. Initially, the …
underlying molecular mechanisms were explored in the present study. Initially, the …
Cytoplasmic YAP expression is associated with prolonged survival in patients with lung adenocarcinomas and epidermal growth factor receptor tyrosine kinase …
PL Sun, JE Kim, SB Yoo, H Kim, Y Jin, S Jheon… - Annals of surgical …, 2014 - Springer
Background Yes-associated protein (YAP) has been reported to be associated with the
prognosis of various cancers and also to affect epidermal growth factor receptor–tyrosine …
prognosis of various cancers and also to affect epidermal growth factor receptor–tyrosine …
[HTML][HTML] The prognostic value of YAP1 on clinical outcomes in human cancers
Y Wu, Y Hou, P Xu, Y Deng, K Liu, M Wang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: As an important downstream factor in the Hippo pathway, yes-associated
protein 1 (YAP1) has been detected to be elevated in various cancers and demonstrated to …
protein 1 (YAP1) has been detected to be elevated in various cancers and demonstrated to …
Overexpression of YAP1 is correlated with progression, metastasis and poor prognosis in patients with gastric carcinoma
X Hu, Y Xin, Y Xiao, J Zhao - Pathology & Oncology Research, 2014 - Springer
YAP1 is overexpressed in numerous cancers, but its molecular mechanism in the
carcinogenesis and clinic significance in tumor diagnosis and prognosis remains to be …
carcinogenesis and clinic significance in tumor diagnosis and prognosis remains to be …
Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder
JY Liu, YH Li, HX Lin, YJ Liao, SJ Mai, ZW Liu… - BMC cancer, 2013 - Springer
Background Yes-associated protein 1 (YAP 1), the nuclear effector of the Hippo pathway, is
a key regulator of organ size and a candidate human oncogene in multiple tumors …
a key regulator of organ size and a candidate human oncogene in multiple tumors …