Molecular targeted NIR-II probe for image-guided brain tumor surgery
Optical imaging strategies for improving delineation of glioblastoma (GBM) is highly desired
for guiding surgeons to distinguish cancerous tissue from healthy and precious brain tissue …
for guiding surgeons to distinguish cancerous tissue from healthy and precious brain tissue …
[HTML][HTML] IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
S Kurbegovic, K Juhl, KK Sørensen, J Leth… - Theranostics, 2021 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is a devastating cancer with basically no curative treatment. Even with
aggressive treatment, the median survival is disappointing 14 months. Surgery remains the …
aggressive treatment, the median survival is disappointing 14 months. Surgery remains the …
Rational design of a super-contrast NIR-II fluorophore affords high-performance NIR-II molecular imaging guided microsurgery
In vivo molecular imaging in the “transparent” near-infrared II (NIR-II) window has
demonstrated impressive benefits in reaching millimeter penetration depths with high …
demonstrated impressive benefits in reaching millimeter penetration depths with high …
Molecular cancer imaging in the second near‐infrared window using a renal‐excreted NIR‐II fluorophore‐peptide probe
In vivo molecular imaging of tumors targeting a specific cancer cell marker is a promising
strategy for cancer diagnosis and imaging guided surgery and therapy. While targeted …
strategy for cancer diagnosis and imaging guided surgery and therapy. While targeted …
Exploiting molecular probes to perform near‐infrared fluorescence‐guided surgery
Near‐infrared (NIR) fluorescence imaging can provide real‐time navigation for surgeons to
discriminate boundaries between lesions and healthy tissue, which serves as a promising …
discriminate boundaries between lesions and healthy tissue, which serves as a promising …
Tumor-homing peptide-based NIR-II probes for targeted spontaneous breast tumor imaging
H Zhou, S Li, X Zeng, M Zhang, L Tang, Q Li… - Chinese Chemical …, 2020 - Elsevier
Fluorescence imaging in the second near-infrared window (NIR-II, 1000–1700 nm) is a
promising modality for real-time imaging of cancer and image-guided surgery with superior …
promising modality for real-time imaging of cancer and image-guided surgery with superior …
A Cy5. 5-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice
K Chen, LP Yap, R Park, X Hui, K Wu, D Fan, X Chen… - Amino acids, 2012 - Springer
Near-infrared (NIR) fluorescence optical imaging is an emerging imaging technique for
studying diseases at the molecular level. Optical imaging with a NIR emitting fluorophore for …
studying diseases at the molecular level. Optical imaging with a NIR emitting fluorophore for …
Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions
ALR de Souza, K Marra, J Gunn, KS Samkoe… - Molecular Imaging and …, 2017 - Springer
Purpose Fluorescence guidance in surgical oncology provides the potential to realize
enhanced molecular tumor contrast with dedicated targeted tracers, potentially with a …
enhanced molecular tumor contrast with dedicated targeted tracers, potentially with a …
Near‐infrared‐II molecular dyes for cancer imaging and surgery
Fluorescence bioimaging affords a vital tool for both researchers and surgeons to
molecularly target a variety of biological tissues and processes. This review focuses on …
molecularly target a variety of biological tissues and processes. This review focuses on …
700-nm zwitterionic near-infrared fluorophores for dual-channel image-guided surgery
Purpose The purpose of this study was to develop a family of 700-nm zwitterionic
pentamethine indocyanine near-infrared fluorophores that would permit dual-channel image …
pentamethine indocyanine near-infrared fluorophores that would permit dual-channel image …