Reactive oxygen species (ROS) are products of normal cellular metabolism and are known
to act as second messengers. Under physiological conditions, ROS participate in …

Reactive oxygen species (ROS), either derived from exogenous sources or overproduced
endogenously, can disrupt the body's antioxidant defenses leading to compromised redox …

The lung is a delicate organ with a large surface area that is continuously exposed to the
external environment, and is therefore highly vulnerable to exogenous sources of oxidative …

As eukaryotic life evolved, so too did the need for a source of energy that meets the
requirements of complex organisms. Oxygen provides this vast potential energy source, but …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated
throughout the human body. Enzymatic and nonenzymatic antioxidants detoxify ROS and …

Globally, respiratory diseases are major cause of disability and mortality, and more
alarmingly, it disproportionately affects developing countries, which is largely attributed to …

Reactive oxygen species (ROS) are well recognized for playing a dual role as both
deleterious and beneficial species. ROS are products of normal cellular metabolism and …

Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

Reactive oxygen and nitrogen species are generated by several inflammatory and structural
cells of the airways. These oxidant species may have important effects on different lung cells …

Reactive species provoke amplification of inflammatory response in the airways and lung
parenchyma causing inhibition of mitochondrial respiration, and lipid, protein, and DNA …