Pharmacotherapy for prevention and treatment of acute respiratory distress syndrome: current and experimental approaches

KJ Bosma, R Taneja, JF Lewis - Drugs, 2010 - Springer
The acute respiratory distress syndrome (ARDS) arises from direct and indirect injury to the
lungs and results in a life-threatening form of respiratory failure in a heterogeneous, critically …

Emerging therapies for treatment of acute lung injury and acute respiratory distress syndrome

KJ Bosma, JF Lewis - Expert Opinion on Emerging Drugs, 2007 - Taylor & Francis
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a life-threatening form of
respiratory failure that affects a heterogeneous population of critically ill patients. Although …

Clinical review: Exogenous surfactant therapy for acute lung injury/acute respiratory distress syndrome-where do we go from here?

A Dushianthan, R Cusack, V Goss, AD Postle… - Critical Care, 2012 - Springer
Acute lung injury and acute respiratory distress syndrome (ARDS) are characterised by
severe hypoxemic respiratory failure and poor lung compliance. Despite advances in clinical …

Exogenous surfactant therapy for ARDS

A Maruscak, JF Lewis - Expert Opinion on Investigational Drugs, 2006 - Taylor & Francis
Regardless of the cause, a common pathophysiological feature of patients with acute
respiratory distress syndrome is a dysfunction of the endogenous surfactant system …

Acute respiratory distress syndrome: pharmacological treatment options in development

RD Hite, PE Morris - Drugs, 2001 - Springer
The acute respiratory distress syndrome (ARDS) is a clinical syndrome with primarily
supportive management options. Despite extensive basic and clinical investigations …

Acute Respiratory Distress Syndrome: 30 Years Later?

O Lesur, Y Berthiaume, G Blaise… - Canadian …, 1999 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) was first described about 30 years ago. Modern
definitions and statements have recently been proposed to describe ARDS accurately, but …

Did reduced alveolar delivery of surfactant contribute to negative results in adults with acute respiratory distress syndrome?

JB Grotberg, M Filoche, DF Willson… - American Journal of …, 2017 - atsjournals.org
The efficacy of surfactant replacement therapy for pediatric and adult lung injuries has been
an ongoing area of investigation for more than 25 years. Surfactant therapy is lifesaving in …

Evolution of treatments for patients with acute lung injury

AM Esper, GS Martin - Expert Opinion on Investigational Drugs, 2005 - Taylor & Francis
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are acute life-
threatening forms of hypoxemic respiratory failure. ALI/ARDS patients require intensive care …

Acute respiratory distress syndrome (ARDS).

TL Petty - Disease-a-month: DM, 1990 - europepmc.org
The acute respiratory distress syndrome (ARDS) is a common clinical catastrophe following
acute lung injury. A multiplicity of clinical states can lead to ARDS. A new classification …

The future of surfactant therapy during ALI/ARDS

JF Lewis, RAW Veldhuizen - Seminars in respiratory and …, 2006 - thieme-connect.com
The importance of pulmonary surfactant in maintaining normal lung function, and the
observations that alterations in endogenous surfactant contribute to the lung dysfunction …