Pharmacokinetic and Pharmacodynamic Analysis of the Oxacephem Antibiotic Flomoxef against Extended-Spectrum β-Lactamase-Producing Enterobacterales from …

M Kusumoto, M Jitsuiki, T Motegi, K Harada - International Journal of …, 2024 - mdpi.com
Flomoxef (FMX) may be a potential alternative to carbapenems for dogs infected with
Enterobacterales-producing extended-spectrum β-lactamase (ESBL-E). However, the …

Pharmacokinetics/Pharmacodynamics Evaluation of Flomoxef against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli In Vitro and In Vivo in a …

S Tashiro, M Hayashi, W Takemura, Y Igarashi… - Pharmaceutical …, 2021 - Springer
Purpose Although flomoxef (FMOX) has attracted substantial attention as an antibiotic
against extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-producing E …

In vitro activity of flomoxef and comparators against Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis producing extended-spectrum β-lactamases in …

Q Yang, H Zhang, J Cheng, Z Xu, Y Xu, B Cao… - International journal of …, 2015 - Elsevier
The objective of this study was to better understand the in vitro activity of flomoxef against
clinical extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. A total of …

In vitro efficacy of humanized regimen of flomoxef against extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae

H Yamashiro, Y Kasamatsu, N Anan… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
This study compared the efficacy of flomoxef with other β-lactam antibiotics against extended-
spectrum β-lactamases (ESBL)-producing bacteria of clinical relevance. First, the …

In vitro activity of flomoxef against extended-spectrum β-lactamase–producing Escherichia coli and Klebsiella pneumoniae in Korea

Y Jung, SS Lee, W Song, HS Kim, Y Uh - Diagnostic Microbiology and …, 2019 - Elsevier
To find an alternative regimen for the treatment of extended-spectrum β-lactamase (EBSL)–
producing Enterobacteriaceae infections, we examined the in vitro activity of flomoxef …

Assessment of urinary pharmacokinetic and pharmacodynamic profiles of faropenem against extended-spectrum β-lactamase-producing Escherichia coli with canine …

K Harada, T Shimizu, N Miyashita… - Access …, 2019 - microbiologyresearch.org
This study was carried out to investigate the urinary pharmacokinetics and
pharmacodynamics of faropenem administered orally at 5 mg kg− 1 in six healthy dogs to …

Pharmacokinetic-pharmacodynamic analysis of cefmetazole against extended-spectrum β-lactamase-producing Enterobacteriaceae in dogs using Monte Carlo …

M Kusumoto, T Motegi, H Uno, M Yokono… - Frontiers in Veterinary …, 2023 - frontiersin.org
The spread of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) is a
serious concern in companion animal medicine owing to their ability to develop multidrug …

In vitro Activity of Cefmetazole and Flomoxef among Extended-Spectrum Beta-Lactamase producing Enterobacterales.

K Iio, H Hagiya, T Higashionna, F Otsuka - The new Microbiologica, 2024 - europepmc.org
In this age of antimicrobial resistance (AMR), improving treatment using existing antibiotics
is desirable. Extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales (ESBL …

In-vitro activity of oxymino-cephalosporins with and without sulbactam against Class A Extended-spectrum β-lactamase producing E. coli

F Kolayli, C Semiz, H Vahaboğlu - Journal of Microbiology and …, 2011 - dergipark.org.tr
Objectives: The primary aim of this study was to determine the activities of ceftazidime and
cefepime combined to sulbactam against class A extended-spectrum β lactamases (ESBLs) …

[PDF][PDF] Evaluation of antibacterial activities of flomoxef against ESBL producing Enterobacteriaceae analyzed by Monte Carlo simulation

A Ito, YM Tatsumi, T Wajima, R Nakamura, M Tsuji - Jpn J Antibiot, 2013 - antibiotics.or.jp
The growing number of infection caused by extended-spectrum/-lactamase (ESBL)
producing pathogens has prompted a more rational use of available antibiotics because of …