Stopping antidepressants can be challenging due to the high rate of discontinuation
symptoms. Patients with antidepressant discontinuation syndrome (ADS) commonly …

Antidepressant drugs are prescribed to patients with depressive, anxiety disorders, and
other conditions. Evidence about antidepressant discontinuation syndrome (ADS) and …

Recent media reports have refocused attention on the syndromic manifestation experienced
by some patients as they discontinue their antidepressant medication (“discontinuation …

Objective Antidepressants are at best 50–55% effective. Non‐compliance and the
antidepressant discontinuation syndrome (ADS) are causally related yet poorly appreciated …

Discontinuation symptoms are recognised with tricyclic antidepressants, monoamine
oxidase inhibitors, selective serotonin reuptake inhibitors (SSRIs) and miscellaneous …

Background The topic of patients' discontinuing use of antidepressants has received
increasing attention. Patients and physicians can encounter challenges regarding the three …

To minimize the symptoms of antidepressant discontinuation, gradual tapering is necessary
for all serotonin reuptake inhibitors (SRIs) except fluoxetine, which has an extended half-life …

Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-
described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors …

Depressive disorders require long-term treatment with antidepressants, psychotherapy, or
both. The goal of antidepressant therapy is complete remission of symptoms and return to …

Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …