[HTML][HTML] Aptamer-functionalized nano-biosensors

TC Chiu, CC Huang - Sensors, 2009 - mdpi.com
Nanomaterials have become one of the most interesting sensing materials because of their
unique size-and shape-dependent optical properties, high surface energy and surface-to …

Recent advancements of aptamers in cancer therapy

S Venkatesan, K Chanda, MM Balamurali - ACS omega, 2023 - ACS Publications
Aptamers are chemical antibodies possessing the capability of overcoming the limitations
posed by conventional antibodies, particularly for diagnostic, therapeutic, and theranostic …

Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …

Aptamer-guided nanomedicines for anticancer drug delivery

W Alshaer, H Hillaireau, E Fattal - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are versatile nucleic acid-based macromolecules characterized by their high
affinity and specificity to a specific target. Taking advantage of such binding properties …

Molecular aptamers for drug delivery

W Tan, H Wang, Y Chen, X Zhang, H Zhu, C Yang… - Trends in …, 2011 - cell.com
The active targeting of drugs in a cell-, tissue-or disease-specific manner represents a
potentially powerful technology with widespread applications in medicine, including the …

DNA aptamer based nanodrugs: molecular engineering for efficiency

S Cansiz, L Zhang, C Wu, Y Wu, IT Teng… - Chemistry–An Asian …, 2015 - Wiley Online Library
In the past two decades, the study of cancer therapy has gradually advanced to the “nano”
era. Numerous novel nanomaterials armed with unique physical properties have been …

[HTML][HTML] Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

[HTML][HTML] Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery

M Narwade, A Shaikh, KR Gajbhiye, P Kesharwani… - Biomaterials …, 2023 - Springer
The non-specificity of standard anticancer therapies has profound detrimental
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …

[HTML][HTML] Aptamers: active targeting ligands for cancer diagnosis and therapy

X Wu, J Chen, M Wu, JX Zhao - Theranostics, 2015 - ncbi.nlm.nih.gov
Aptamers, including DNA, RNA and peptide aptamers, are a group of promising recognition
units that can specifically bind to target molecules and cells. Due to their excellent specificity …

Nanotechnology and aptamers: applications in drug delivery

E Levy-Nissenbaum, AF Radovic-Moreno… - Trends in …, 2008 - cell.com
Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being
used in several novel nanobiomedical applications. Aptamers are characterized by high …