Recent advancements of aptamers in cancer therapy
S Venkatesan, K Chanda, MM Balamurali - ACS omega, 2023 - ACS Publications
Aptamers are chemical antibodies possessing the capability of overcoming the limitations
posed by conventional antibodies, particularly for diagnostic, therapeutic, and theranostic …
posed by conventional antibodies, particularly for diagnostic, therapeutic, and theranostic …
Recent progress in aptamer discoveries and modifications for therapeutic applications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …
Aptamer-guided nanomedicines for anticancer drug delivery
Aptamers are versatile nucleic acid-based macromolecules characterized by their high
affinity and specificity to a specific target. Taking advantage of such binding properties …
affinity and specificity to a specific target. Taking advantage of such binding properties …
Molecular aptamers for drug delivery
The active targeting of drugs in a cell-, tissue-or disease-specific manner represents a
potentially powerful technology with widespread applications in medicine, including the …
potentially powerful technology with widespread applications in medicine, including the …
DNA aptamer based nanodrugs: molecular engineering for efficiency
In the past two decades, the study of cancer therapy has gradually advanced to the “nano”
era. Numerous novel nanomaterials armed with unique physical properties have been …
era. Numerous novel nanomaterials armed with unique physical properties have been …
[HTML][HTML] Detection and beyond: Challenges and advances in aptamer-based biosensors
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …
detection, newly emerging requirements including a real-time detection ability and in-field …
[HTML][HTML] Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery
The non-specificity of standard anticancer therapies has profound detrimental
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …
[HTML][HTML] Aptamers: active targeting ligands for cancer diagnosis and therapy
Aptamers, including DNA, RNA and peptide aptamers, are a group of promising recognition
units that can specifically bind to target molecules and cells. Due to their excellent specificity …
units that can specifically bind to target molecules and cells. Due to their excellent specificity …
Nanotechnology and aptamers: applications in drug delivery
E Levy-Nissenbaum, AF Radovic-Moreno… - Trends in …, 2008 - cell.com
Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being
used in several novel nanobiomedical applications. Aptamers are characterized by high …
used in several novel nanobiomedical applications. Aptamers are characterized by high …