Nanotechnology and aptamers: applications in drug delivery
E Levy-Nissenbaum, AF Radovic-Moreno… - Trends in …, 2008 - cell.com
Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being
used in several novel nanobiomedical applications. Aptamers are characterized by high …
used in several novel nanobiomedical applications. Aptamers are characterized by high …
Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation
Aptamer nanomedicine, including therapeutic aptamers and aptamer nanocomplexes, is
beginning to fulfill its potential in both clinical trials and preclinical studies. Especially in …
beginning to fulfill its potential in both clinical trials and preclinical studies. Especially in …
Recent advances in aptamer-based targeted drug delivery systems for cancer therapy
F Gao, J Yin, Y Chen, C Guo, H Hu… - Frontiers in Bioengineering …, 2022 - frontiersin.org
The past decade has become an important strategy in precision medicine for the targeted
therapy of many diseases, expecially various types of cancer. As a promising targeted …
therapy of many diseases, expecially various types of cancer. As a promising targeted …
The application of aptamers in cancer research: an up-to-date review
M Hu, K Zhang - Future Oncology, 2013 - Taylor & Francis
Aptamers are nucleic acid ligands that are generated by molecular evolution to bind with
high affinities and specificities to a large variety of targets, which make them attractive tools …
high affinities and specificities to a large variety of targets, which make them attractive tools …
[HTML][HTML] Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine
Conventional anticancer therapies, such as chemo-and/or radio-therapy are often unable to
completely eradicate cancers due to abnormal tumor microenvironment, as well as …
completely eradicate cancers due to abnormal tumor microenvironment, as well as …
[HTML][HTML] Aptamers used for molecular imaging and theranostics-recent developments
L Bohrmann, T Burghardt, C Haynes, K Saatchi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aptamers are single stranded oligonucleotides that fold into three dimensional structures
and are able to recognize a variety of molecular targets. Due to the similarity to antibodies …
and are able to recognize a variety of molecular targets. Due to the similarity to antibodies …
Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy
Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
Nucleic acid aptamers in cancer research, diagnosis and therapy
Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
[HTML][HTML] Progress in aptamer-mediated drug delivery vehicles for cancer targeting and its implications in addressing chemotherapeutic challenges
J Zhu, H Huang, S Dong, L Ge, Y Zhang - Theranostics, 2014 - ncbi.nlm.nih.gov
Aptamers are novel oligonucleotides with flexible three-dimensional configurations that
recognize and bind to their cognate targets, including tumor surface receptors, in a high …
recognize and bind to their cognate targets, including tumor surface receptors, in a high …
Nanomaterial-assisted aptamers for optical sensing
Aptamers are single-strand DNA or RNA selected in vitro that bind specifically with a broad
range of targets from metal ions, organic molecules, to proteins, cells and microorganisms …
range of targets from metal ions, organic molecules, to proteins, cells and microorganisms …