Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being
used in several novel nanobiomedical applications. Aptamers are characterized by high …

Aptamer nanomedicine, including therapeutic aptamers and aptamer nanocomplexes, is
beginning to fulfill its potential in both clinical trials and preclinical studies. Especially in …

The past decade has become an important strategy in precision medicine for the targeted
therapy of many diseases, expecially various types of cancer. As a promising targeted …

Aptamers are nucleic acid ligands that are generated by molecular evolution to bind with
high affinities and specificities to a large variety of targets, which make them attractive tools …

Conventional anticancer therapies, such as chemo-and/or radio-therapy are often unable to
completely eradicate cancers due to abnormal tumor microenvironment, as well as …

Aptamers are single stranded oligonucleotides that fold into three dimensional structures
and are able to recognize a variety of molecular targets. Due to the similarity to antibodies …

Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …

Aptamers are novel oligonucleotides with flexible three-dimensional configurations that
recognize and bind to their cognate targets, including tumor surface receptors, in a high …

Aptamers are single-strand DNA or RNA selected in vitro that bind specifically with a broad
range of targets from metal ions, organic molecules, to proteins, cells and microorganisms …