Aptamer-conjugated carbon-based nanomaterials for cancer and bacteria theranostics: A review

S Sargazi, ER Simge, A Mobashar, SS Gelen… - Chemico-biological …, 2022 - Elsevier
Aptamers are single-stranded oligonucleotides that link to various substrates with great
affinity and selectivity, including small molecules, peptides, proteins, cells, and tissues. For …

Aptamer chemistry

P Röthlisberger, M Hollenstein - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …

Aptamer based recognition of cancer cells: Recent progress and challenges in bioanalysis

HK Kordasht, M Hasanzadeh - Talanta, 2020 - Elsevier
Rapid and accurate monitoring of cancer cells with high sensitivity is essential for a
successful cancer treatment. As high-affinity nucleic acid ligands, aptamers can improve the …

Nanoparticles application in high sensitive aptasensor design

F Charbgoo, F Soltani, SM Taghdisi, K Abnous… - TrAC Trends in …, 2016 - Elsevier
In an effort to achieve high sensitive and selective detection approaches, numerous
materials are currently being explored for their application in sensing systems …

[HTML][HTML] Recent advances in aptamer-based therapeutic strategies for targeting cancer stem cells

B Liu, J Liu, X Hu, W Xiang, W Hou, C Li, J Wang… - Materials Today Bio, 2023 - Elsevier
Cancer stem cells (CSCs) are believed to be the main cause of chemotherapy resistance
and tumor relapse. Various therapeutic strategies to eliminate CSCs have been developed …

Circular Bivalent Aptamers Enable in Vivo Stability and Recognition

H Kuai, Z Zhao, L Mo, H Liu, X Hu, T Fu… - Journal of the …, 2017 - ACS Publications
Aptamers are powerful candidates for molecular imaging and targeted therapy of cancer
based on such appealing features as high binding affinity, high specificity, site-specific …

Aptamer-programmed DNA nanodevices for advanced, targeted cancer theranostics

S Walia, AR Chandrasekaran… - ACS Applied Bio …, 2021 - ACS Publications
DNA has been demonstrated to be a versatile material for construction at the nanoscale.
DNA nanodevices are highly programmable and allow functionalization with multiple entities …

Functional DNA molecules enable selective and stimuli-responsive nanoparticles for biomedical applications

L Li, H Xing, J Zhang, Y Lu - Accounts of chemical research, 2019 - ACS Publications
Conspectus Nanoparticles (NPs) have enormous potential to improve disease diagnosis
and treatment due to their intrinsic electronic, optical, magnetic, mechanical, and …

Aptamer applications for targeted cancer therapy

AS Barbas, J Mi, BM Clary, RR White - Future oncology, 2010 - Taylor & Francis
Aptamers are single-stranded DNA or RNA oligonucleotides that assume specific 3D
structures and bind to target molecules with high affinity. The unique specificity of aptamers …

Progress and challenges in developing aptamer-functionalized targeted drug delivery systems

F Jiang, B Liu, J Lu, F Li, D Li, C Liang, L Dang… - International journal of …, 2015 - mdpi.com
Aptamers, which can be screened via systematic evolution of ligands by exponential
enrichment (SELEX), are superior ligands for molecular recognition due to their high …