Aptamer-conjugated carbon-based nanomaterials for cancer and bacteria theranostics: A review
Aptamers are single-stranded oligonucleotides that link to various substrates with great
affinity and selectivity, including small molecules, peptides, proteins, cells, and tissues. For …
affinity and selectivity, including small molecules, peptides, proteins, cells, and tissues. For …
Aptamer chemistry
P Röthlisberger, M Hollenstein - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …
Aptamer based recognition of cancer cells: Recent progress and challenges in bioanalysis
HK Kordasht, M Hasanzadeh - Talanta, 2020 - Elsevier
Rapid and accurate monitoring of cancer cells with high sensitivity is essential for a
successful cancer treatment. As high-affinity nucleic acid ligands, aptamers can improve the …
successful cancer treatment. As high-affinity nucleic acid ligands, aptamers can improve the …
Nanoparticles application in high sensitive aptasensor design
In an effort to achieve high sensitive and selective detection approaches, numerous
materials are currently being explored for their application in sensing systems …
materials are currently being explored for their application in sensing systems …
[HTML][HTML] Recent advances in aptamer-based therapeutic strategies for targeting cancer stem cells
B Liu, J Liu, X Hu, W Xiang, W Hou, C Li, J Wang… - Materials Today Bio, 2023 - Elsevier
Cancer stem cells (CSCs) are believed to be the main cause of chemotherapy resistance
and tumor relapse. Various therapeutic strategies to eliminate CSCs have been developed …
and tumor relapse. Various therapeutic strategies to eliminate CSCs have been developed …
Circular Bivalent Aptamers Enable in Vivo Stability and Recognition
Aptamers are powerful candidates for molecular imaging and targeted therapy of cancer
based on such appealing features as high binding affinity, high specificity, site-specific …
based on such appealing features as high binding affinity, high specificity, site-specific …
Aptamer-programmed DNA nanodevices for advanced, targeted cancer theranostics
S Walia, AR Chandrasekaran… - ACS Applied Bio …, 2021 - ACS Publications
DNA has been demonstrated to be a versatile material for construction at the nanoscale.
DNA nanodevices are highly programmable and allow functionalization with multiple entities …
DNA nanodevices are highly programmable and allow functionalization with multiple entities …
Functional DNA molecules enable selective and stimuli-responsive nanoparticles for biomedical applications
Conspectus Nanoparticles (NPs) have enormous potential to improve disease diagnosis
and treatment due to their intrinsic electronic, optical, magnetic, mechanical, and …
and treatment due to their intrinsic electronic, optical, magnetic, mechanical, and …
Aptamer applications for targeted cancer therapy
Aptamers are single-stranded DNA or RNA oligonucleotides that assume specific 3D
structures and bind to target molecules with high affinity. The unique specificity of aptamers …
structures and bind to target molecules with high affinity. The unique specificity of aptamers …
Progress and challenges in developing aptamer-functionalized targeted drug delivery systems
Aptamers, which can be screened via systematic evolution of ligands by exponential
enrichment (SELEX), are superior ligands for molecular recognition due to their high …
enrichment (SELEX), are superior ligands for molecular recognition due to their high …