The ability to self-assemble one-dimensional DNA building blocks into two-and three-
dimensional nanostructures via DNA/RNA nanotechnology has led to broad applications in …

Cancer is the second leading cause of death worldwide. Researchers have been working
hard on investigating not only improved therapeutics but also on early detection methods …

Nanomaterials have been exploited extensively to fabricate various biosensors for clinical
diagnostics and food & environmental monitoring. These materials in conjugation with highly …

The ability to probe low-abundance biomolecules or transport a high-load drug in target
cells is essential for biology and theranostics. We develop a novel activatable theranostic …

Aptamers are single-stranded oligonucleotides that fold into well-defined three-dimensional
shapes, allowing them to bind their targets with high affinity and specificity. They can be …

We review advances in the development and the application of optical biosensing systems
based on aptamers. Aptamers exhibit advantages as molecular recognition elements for …

Nucleic acid aptamers, which are generated by a novel technique called SELEX (systematic
evolution of ligands by exponential enrichment), have recently attracted significant attention …

Aptamers are single-stranded oligonucleotides that specifically bind and interact with their
corresponding targets, including proteins and cells, through unique three-dimensional …

Highlights•The development of DNA aptamers parallels that of personalized medicine.•Both
aptamer-functionalized nanomaterials and DNA nanostructures have been developed.•They …

Aptamers are an interesting class of molecules that have potential in many facets of human
health. They are characterized by high affinity and specificity to their targets, are small in …