Targeted diagnostics and therapeutics for individualized patient management

S Waldman, A Terzic - Biomarkers in Medicine, 2007 - Taylor & Francis
Advances in deconvoluting complex disease processes, enabling genomic, proteomic,
metabolomic and imaging technologies, highthroughput drug discovery and development …

Translational biomarkers: from discovery and development to clinical practice

M Subramanyam, J Goyal - Drug Discovery Today: Technologies, 2016 - Elsevier
The refinement of disease taxonomy utilizing molecular phenotypes has led to significant
improvements in the precision of disease diagnosis and customization of treatment options …

Translational medicine individualizes healthcare discovery, development and delivery

SA Waldman, A Terzic - Biomarkers in Medicine, 2013 - Taylor & Francis
Individualized patient management is rapidly expanding, fueled by unprecedented
innovation that spans modern medical discovery, development and delivery [1, 2]. This next …

Opportunities and challenges of disease biomarkers: a new section in the journal of translational medicine

X Wang, PA Ward - Journal of Translational Medicine, 2012 - Springer
Disease biomarkers are defined to diagnose various phases of diseases, monitor severities
of diseases and responses to therapies, or predict prognosis of patients. Disease-specific …

[HTML][HTML] Molecular Diagnostics: at the nexus of individualized medicine, health care delivery, and public policy

SA Waldman, A Terzic - Clinical and translational science, 2009 - ncbi.nlm.nih.gov
Advances in decoding integrated biological processes; the surge in enabling technologies
including the highthroughput platforms of genomics, proteomics, and metabolomics; and the …

Biomarkers: Delivering on the expectation of molecularly driven, quantitative health

JL Wilson, RB Altman - Experimental Biology and Medicine, 2018 - journals.sagepub.com
Biomarkers are the pillars of precision medicine and are delivering on expectations of
molecular, quantitative health. These features have made clinical decisions more precise …

[图书][B] Handbook of biomarkers and precision medicine

C Carini, M Fidock, A van Gool - 2019 - api.taylorfrancis.com
Today, the practice of medicine remains largely empirical. Physicians generally rely on
matching patterns in patient history, symptoms, and laboratory data to make the diagnosis …

[PDF][PDF] Biomarkers in drug development and patient care

M Svinte, B Robson, M Hehenberger - Burrill Personalized Medicine …, 2007 - academia.edu
Patients expect medical treatments that work and are safe and “right” for them as individuals.
Biomarkers can help bio-pharmaceutical and diagnostics companies to focus more on …

Making biomarkers relevant to healthcare innovation and precision medicine

NI Al-Dewik, SN Younes, MM Essa, S Pathak… - Processes, 2022 - mdpi.com
Translational medicine, the exchange between laboratory (bench) and the clinic (bedside),
is decidedly taking on a vital role. Many companies are now focusing on a translational …

Patient-centric clinical pharmacology advances the path to personalized medicine

SA Waldman, A Terzic - Biomarkers in Medicine, 2011 - Taylor & Francis
drugs? This focus on drug action and disposition provided the fundamental algorithms of
personalized medicine in which the right drug is used in the right patient at the right dose (for …