Aim: Oxidative stress plays a critical role in the pathogenic cascade leading to neuronal
degeneration in AD. Consequently, the induction of endogenous antioxidative proteins by …

Alzheimer's disease (AD) is the most common form of dementia. Glucagon-like peptide-1
(GLP-1) gives a new genre in therapeutic targets for intervention in AD with its neurotrophic …

Perinatal hypoxic-ischemia (HI) is a leading cause of acute mortality and neurologic
complications in newborns. Geniposide, a natural product extracted from the herb Gardenia …

We aimed to investigate whether geniposide, a main component extracted from Gardenia
jasminoides Ellis fruit, could exert neuroprotective functions against traumatic brain injury …

Aim: To explore the role of activation of glucagon-like peptide 1 receptor (GLP-1R) and its
relative cell signaling pathway in the cytoprotection of geniposide. Methods: Cell viability …

Geniposide, an iridoid glycoside isolated from Gardenia, has neuroprotective activities
against oxidative stress and inflammation. The present study investigated the in vivo …

Context: Genistein, one of the isoflavones derived from soybean seeds, has been reported
to exert multiple bioactivities. However, the mechanism of its action on the central nervous …

With the advanced discoveries in the field of pathogenesis, a series of cerebral diseases,
such as cerebral ischaemia, Alzheimer's disease, and depression, have been found to have …

Background Formaldehyde can induce misfolding and aggregation of Tau protein and β
amyloid protein, which are characteristic pathological features of Alzheimer's disease (AD) …

Parkinson's disease (PD) is a chronic neurodegenerative disease, and there is no cure for it
at present. We tested the drug Geniposide, an active component of Gardenia jasminoides …