Oxidative stress is defined as an imbalance between generation of reactive oxygen species
(ROS) and decreased antioxidant defense systems. Oxidative stress develops particularly in …

Oxidative stress has long been known as a pathogenic factor of ulcerative colitis (UC) and
colitis‐associated colorectal cancer (CAC), but the effects of secondary carbonyl lesions …

The chronic inflammatory bowel disease ulcerative colitis (UC) occurs commonly in the US
and other Western countries, but its etiology is unknown. An association between UC and an …

Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

It has been established that there is a relationship between chronic inflammation and cancer
development. The constant colonic inflammation typical of inflammatory bowel diseases is …

Ulcerative colitis is an idiopathic, chronic and relapsing inflammatory bowel disease, which
elicits the risk of colorectal cancer, the third most common malignancy in humans. It has …

ABSTRACT Background/Aims: Elevated oxidative status has been found in many types of
cancer cells. Recent studies have shown that the enzymatic product of thymidine …

Oxygen free radicals in excessively high amounts are all very reactive chemically and can
impose a detrimental influence on living organisms by provoking “oxidative stress” that can …

This review will focus on published human studies on oxidative stress and DNA damage in
inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease, assessing …

Ulcerative colitis (UC) is characterized by repeated flare-ups of inflammation that can lead to
oncogenic insults to the colonic epithelial. UC-associated carcinogenesis presents a …