Dopamine D2 receptors (Rs) and adenosine A2ARs are coexpressed on striatopallidal
neurons, where they mediate opposing actions. In agreement with the idea that D2Rs …

The A2AR is largely coexpressed with D2Rs and enkephalin mRNA in the striatum where it
modulates dopaminergic activity. Activation of the A2AR antagonizes D2R-mediated …

Since high-affinity adenosine A2 receptors (A2a) are localized exclusively in dopamine-rich
regions in the central nervous system and mediate inhibition of locomotor activity, we have …

Adenosine is known to modulate dopamine responses in several brain areas. Here, we
show that tonic activation of adenosine receptors is able to impede desensitization of D1 …

The possible molecular basis for the previously described antagonistic interactions between
adenosine A1 receptors (A1R) and dopamine D1 receptors (D1R) in the brain have been …

Neurochemical and pharmcological evidence obtained over the past 300 yr has indicated
that adenosine and dopamine interact functionally in the basal ganglia and that such …

An interaction between adenosine A 2A and dopamine D 2 receptors has been
demonstrated previously. It is generally found that agonist treatment internalizes receptors …

Antagonistic interactions between adenosine A2a and dopamine D2 receptors and between
adenosine A1 and dopamine D1 receptors have been previously found in the basal ganglia …

BEHAVIOURAL, AND biochemical evidence for the existence of a powerful specific
postsynaptic interaction between adenosine A 1, and dopamine D 1 receptors in the …

Human adenosine A2A and rat dopamine D2 receptors (A2A and D2 receptors) were co-
transfected in Chinese hamster ovary (CHO) cells to study the interactions between two …