Randomized phase III study of chemoradiation with or without amifostine for patients with favorable performance status inoperable stage II-III non-small cell lung …

R Komaki, JS Lee, B Kaplan, P Allen, JF Kelly… - Seminars in radiation …, 2002 - Elsevier
A prospective randomized study was conducted to determine whether amifostine (Ethyol)
reduces the rate of severe esophagitis and hematologic and pulmonary toxicity associated …

Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non–small-cell lung cancer: report of a randomized comparative …

R Komaki, JS Lee, L Milas, HK Lee, FV Fossella… - International Journal of …, 2004 - Elsevier
PURPOSE: To determine the ability of amifostine to reduce the severity and/or incidence of
the acute toxicities of concurrent chemotherapy and radiotherapy (RT) for non–small-cell …

Phase II: trial of twice weekly amifostine in patients with non-small cell lung cancer treated with chemoradiotherapy

M Werner-Wasik, RS Axelrod, DP Friedland… - Seminars in radiation …, 2002 - Elsevier
Twenty-four patients with non-small cell lung cancer received induction chemotherapy
(paclitaxel, carboplatin) followed by concurrent thoracic irradiation (RT) and weekly …

Radiotherapy or chemotherapy followed by radiotherapy with or without amifostine in locally advanced lung cancer

D Anlonadou - Seminars in Radiation Oncology, 2002 - Elsevier
Radiotherapy (RT) or radiochemotherapy is the treatment of choice for patients with
medically or technically inoperable non-small cell lung cancer (NSCLC) localized to the …

Randomized double-blind trial of combined modality treatment with or without amifostine in unresectable stage III non–small-cell lung cancer

SS Leong, EH Tan, KW Fong, E Wilder-Smith… - Journal of clinical …, 2003 - ascopubs.org
Purpose: Greater toxicities have been recognized to be a consequence of combined
chemotherapy and radiotherapy in the treatment of locally advanced non–small-cell lung …

Randomized phase III trial of radiation treatment±amifostine in patients with advanced-stage lung cancer

D Antonadou, N Coliarakis, M Synodinou… - International Journal of …, 2001 - Elsevier
Purpose: This multicenter trial investigated whether daily pretreatment with amifostine (A)
could reduce the incidence of acute and late lung toxicity and esophagitis without affecting …

Preliminary report on reduction of esophagitis by amifostine in patients with non–small-cell lung cancer treated with chemoradiotherapy

M Werner-Wasik, RS Axelrod, DP Friedland, W Hauck… - Clinical lung cancer, 2001 - Elsevier
Esophagitis is a major toxicity of chemoradiotherapy for lung cancer. Twenty-four patients
with non–smallcell lung cancer received induction chemotherapy (paclitaxel/carboplatin) …

Effect of amifostine on toxicities associated with radiochemotherapy in patients with locally advanced non–small-cell lung cancer

D Antonadou, N Throuvalas, A Petridis… - International Journal of …, 2003 - Elsevier
PURPOSE: Radiochemotherapy (RCT) is an effective treatment for locally advanced non–
small-cell lung cancer (NSCLC), but can be limited by acute and late toxicities (esophagitis …

The addition of amifostine to carboplatin and paclitaxel based chemoradiation in locally advanced non-small cell lung cancer: long-term follow-up of Radiation …

YR Lawrence, R Paulus, C Langer, M Werner-Wasik… - Lung Cancer, 2013 - Elsevier
INTRODUCTION: We report the long-term results of RTOG 9801, a randomized trial
investigating the ability of amifostine, a radioprotector, to reduce chemoradiation-induced …

Amifostine reduces radiochemotherapy-induced toxicities in patients with locally advanced non-small cell lung cancer

D Antonadou, A Petridis, M Synodinou… - Seminars in …, 2003 - Elsevier
Radiochemotherapy (RCT) is an effective treatment for locally advanced non-small cell lung
cancer, but can be limited by acute and late toxicities (esophagitis, pneumonitis, and …