Background Proton pump inhibitor (PPI) use has been reported to be associated with liver
damage and might possibly be carcinogenic. Aims We examined whether long‐term PPI use …

Researchers have hypothesized that the long‐term use of proton pump inhibitors (PPIs) can
increase the risk of developing cancer. However, the association between PPI use and …

(1) Background: The association between proton pump inhibitor (PPI) use and
hepatocellular carcinoma (HCC) has been controversial, especially in the general …

Background: Worldwide, proton pump inhibitors (PPIs) are commonly used for the treatment
of peptic ulcer and gastro-esophageal reflux disease. Recently, concern has arisen over the …

Background Epidemiological studies investigating the use of proton pump inhibitors (PPI) on
the risk of liver cancer and/or mortality among persons with chronic liver disease (CLD) have …

METHODS: We performed a nested case-control study in a large, community-based
integrated healthcare setting. Cases were adults with gastric (n= 1,233), colorectal (n …

Purpose: To investigate the use of proton pump inhibitors (PPIs) and the risk of pancreatic
cancer. Methods: A nested case–control analysis was conducted. Patients with pancreas …

Objectives: Increasing evidence suggested that proton pump inhibitors (PPIs) use might
affect the development of cancers, but previous conclusions remain controversial. Therefore …

Background Proton pump inhibitors (PPI s) and histamine‐2 receptor antagonists (H2 RA s)
are commonly used. PPI s have been shown to promote liver cancer in rats; however, only …

Simple Summary Proton pump inhibitors are commonly prescribed medications for
gastrointestinal disorders, which bring gastric acid down to normal levels. However, the …