Cyclophosphamide (CP)‐induced hepatotoxic manifestations are major concern for patients
undergoing chemotherapy, which often limit its therapeutic utility. Nerolidol (NER) is a …

Hepatotoxicity induced by cyclophosphamide (Cyclo) is a major concern in clinical practice.
This study was designed to investigate the possible cytoprotective effect of natural …

Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …

Oligonol is a low molecular weight polyphenol product derived from lychee fruit by a
manufacturing process. We investigated oligonol's anti-fibrotic effect and the underlying …

Taxifolin (TA) is a natural flavonoid found in many foods and medicinal plants with well-
documented antioxidant and anti-inflammatory properties. Cyclophosphamide (CP) is an …

Hepatic ischemia/reperfusion (HIR) is the most common type of liver injury following several
clinical situations. Modulating oxidative stress and inflammation by Nrf2/HO-1 and …

Oxidative stress is thought to be a key risk factor in the development of hepatic diseases.
Blocking or retarding the reactions of oxidation and the inflammatory process by antioxidants …

Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …

Incidence and prevalence of cancer is an alarming situation globally. For the treatment of
cancer many anticancer drugs have been developed but, unfortunately, their potential …

Cyclophosphamide (CP) is widely used as an immunosuppressive and chemotherapeutic
drug. However, its therapeutic application is restricted by its adverse effects, particularly …