Culturomics Approaches Expand the Diagnostic Accuracy for Sexually Transmitted Infections

EA Wolf, HC Rettig, M Lupatsii, B Schlüter… - International Journal of …, 2021 - mdpi.com
Sexually transmitted infections (STIs) are a major health concern with clinical manifestations
being acknowledged to cause severe reproductive impairment. Research in infectious …

[HTML][HTML] Alterations of Vaginal Microbiota in Women With Infertility and Chlamydia trachomatis Infection

H Chen, L Wang, L Zhao, L Luo, S Min… - Frontiers in Cellular …, 2021 - frontiersin.org
Chlamydia trachomatis (C. trachomatis) is the most common etiological agent of bacterial
sexually transmitted infections (STIs) worldwide and causes serious health sequelae such …

[HTML][HTML] Moving beyond DNA: towards functional analysis of the vaginal microbiome by non-sequencing-based methods

GDS Correia, JR Marchesi, DA MacIntyre - Current Opinion in Microbiology, 2023 - Elsevier
Over the last two decades, sequencing-based methods have revolutionised our
understanding of niche-specific microbial complexity. In the lower female reproductive tract …

An insight into vaginal microbiome techniques

M Sharma, C Chopra, M Mehta, V Sharma… - Life, 2021 - mdpi.com
Background There is a unique microbial community in the female lower genital tract known
as the vaginal microbiota, which varies in composition and density and provides significant …

Current Viewpoint on Female Urogenital Microbiome—The Cause or the Consequence?

M Čeprnja, E Hadžić, D Oros, E Melvan, A Starcevic… - Microorganisms, 2023 - mdpi.com
An increasing amount of evidence implies that native microbiota is a constituent part of a
healthy urinary tract (UT), making it an ecosystem on its own. What is still not clear is …

Integrating compositional and functional content to describe vaginal microbiomes in health and disease

JB Holm, MT France, P Gajer, B Ma, RM Brotman… - Microbiome, 2023 - Springer
Background A Lactobacillus-dominated vaginal microbiome provides the first line of defense
against adverse genital tract health outcomes. However, there is limited understanding of …

[HTML][HTML] Determinants of vaginal microbiota composition

Y Moosa, D Kwon, T De Oliveira… - Frontiers in cellular and …, 2020 - frontiersin.org
There is increasing evidence that the composition of a woman's vaginal microbiota
significantly influences her sexual and reproductive health, including her risk of miscarriage …

[HTML][HTML] Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome …

CM O'Connell, H Brochu, J Girardi, E Harrell… - Microbial Cell, 2019 - ncbi.nlm.nih.gov
Pelvic inflammatory disease (PID) is a female upper genital tract inflammatory disorder that
arises after sexually transmitted bacterial infections (STI). Factors modulating risk for …

Exploring the microbiome in human reproductive tract: high-throughput methods for the taxonomic characterization of microorganisms

E Salas-Espejo, LC Terrón-Camero… - Seminars in …, 2023 - thieme-connect.com
Microorganisms are important due to their widespread presence and multifaceted roles
across various domains of life, ecology, and industries. In humans, they underlie the proper …

Qualitative and quantitative detection of multiple sexually transmitted infection pathogens reveals distinct associations with cervicitis and vaginitis

WT Kang, H Xu, Y Liao, Q Guo, Q Huang… - Microbiology …, 2022 - Am Soc Microbiol
Many diverse pathogens have been discovered from reproductive-tract infections, but the
relationship between the presence and abundance of particular pathogen species and …