The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats

TE Wooters, MT Bardo - Behavioural pharmacology, 2007 - journals.lww.com
In addition to delivering nicotine, tobacco smoke also inhibits monoamine oxidase (MAO).
Although MAO inhibitors (MAOIs) can increase nicotine self-administration in rodents, the …

Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats

K Guillem, C Vouillac, MR Azar… - European Journal of …, 2006 - Wiley Online Library
Although nicotine is considered to be responsible for the addictive properties of tobacco,
growing evidence underlines the importance of non‐nicotine components in smoking …

Transient behavioral sensitization to nicotine becomes long-lasting with monoamine oxidases inhibitors

AS Villégier, G Blanc, J Glowinski, JP Tassin - … Biochemistry and Behavior, 2003 - Elsevier
Drugs of abuse, such as d-amphetamine or nicotine, are generally considered as acting
through an increased release of dopamine in a subcortical structure, the nucleus …

Effect of monoamine oxidase inhibition on rewarding effects of nicotine in rodents

CH Kapelewski, DJ Vandenbergh… - Current drug abuse …, 2011 - ingentaconnect.com
Nicotine, the primary psychoactive compound in tobacco, is responsible for the addictive
effects of smoking; however, there is a paucity of information indicating whether the …

[HTML][HTML] Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine

AS Villégier, L Salomon, S Granon… - …, 2006 - nature.com
Although nicotine is generally considered to be the main compound responsible for the
addictive properties of tobacco, experimental data indicate that nicotine does not exhibit all …

Role of training dose in discrimination of nicotine and related compounds by rats

IP Stolerman, HS Garcha, JA Pratt, R Kumar - Psychopharmacology, 1984 - Springer
Rats were trained to discriminate nicotine from saline in a two-bar operant conditioning
procedure with food reinforcement. There was partial generalization to the nicotine …

Nicotine and methamphetamine share discriminative stimulus effects

MB Gatch, E Flores, MJ Forster - Drug and alcohol dependence, 2008 - Elsevier
BACKGROUND: Nicotine and methamphetamine are both abused in similar settings,
sometimes together. Because there are known interactions between central nicotinic …

Discriminative stimulus effects of the nicotine antagonist mecamylamine in rats

HS Garcha, IP Stolerman - Journal of Psychopharmacology, 1993 - journals.sagepub.com
The discriminative stimulus effects of the nicotine antagonist mecamylamine have been
investigated to characterize further its behavioural effects and its interactions with (–) …

Anticholinergic sensitivity following chronic nicotine administration as measured by radial-arm maze performance in rats

ED Levin, JE Rose - Behavioural pharmacology, 1990 - journals.lww.com
Chronic nicotine administration in rats has been previously found to improve choice
accuracy performance of rats in the radial-arm maze. A nicotine-induced choice accuracy …

Effects of central and peripheral nicotinic blockade on human nicotine discrimination

KA Perkins, M Sanders, C Fonte, AS Wilson… - …, 1999 - Springer
Nicotine produces interoceptive stimulus effects in humans, which may be critical in
understanding tobacco use. It has not yet clearly been demonstrated that discrimination of …